Lithium in bipolar disorder: optimizing therapy using prolonged-release formulations

P Girardi, R Brugnoli, G Manfredi, G Sani - Drugs in R&D, 2016 - Springer
Lithium has been a gold standard in the treatment of bipolar disorder (BD) for several
decades. Despite a general reduction in the use of lithium over the past several years, it is …

Treatment of bipolar disorder in a lifetime perspective: is lithium still the best choice?

G Sani, G Perugi, L Tondo - Clinical drug investigation, 2017 - Springer
Lithium preparations have been successfully used to treat bipolar disorder (BD), and remain
the best established long-term treatment for the disorder. In fact, lithium is a cornerstone of …

Why lithium should be used in patients with bipolar disorder? A scoping review and an expert opinion paper

G Sampogna, D Janiri, U Albert, F Caraci… - Expert Review of …, 2022 - Taylor & Francis
Introduction Lithium treatment is considered the gold standard for the long-term
management of bipolar disorder and recurrent unipolar depression. It is also extremely …

Optimal frequency of lithium administration in the treatment of bipolar disorder: clinical and dosing considerations

GS Malhi, M Tanious - CNS drugs, 2011 - Springer
Bipolar disorder is a recurrent chronic illness distinguished by periods of mania and
depression. Lithium has been used for about 60 years as a 'mood stabilizer'for bipolar …

Lithium for bipolar disorder: a review of the recent literature

G Curran, A Ravindran - Expert review of neurotherapeutics, 2014 - Taylor & Francis
Lithium is a commonly prescribed treatment for bipolar disorder. Many early studies on
which its use has been historically based no longer meet current research standards. A …

Lithium treatment—moderate dose use study (LiTMUS) for bipolar disorder: rationale and design

AA Nierenberg, LG Sylvia, AC Leon… - Clinical …, 2009 - journals.sagepub.com
Background Recent data indicate that lithium use for bipolar disorder has declined over the
last decade and that lithium largely has been replaced with alternate, commercially …

Lithium: Updated Human Knowledge Using an Evidence-Based Approach Part I: Clinical Efficacy in Bipolar Disorder.

EM Grandjean, JM Aubry - CNS drugs, 2009 - search.ebscohost.com
Although there has been a decrease in lithium use over several years, it is still
recommended as a first-line mood stabilizer in all recent guidelines. It has been argued that …

Clinically relevant treatment considerations regarding lithium use in bipolar disorder

T Richardson, M Macaluso - Expert opinion on drug metabolism & …, 2017 - Taylor & Francis
Introduction: The goal of this paper is to provide a practical, clinically oriented review of
lithium, a salt widely used to treat mania since the 1870s and formally approved as a mood …

Current perspectives on treatment of bipolar disorder with lithium

PE Keck, SL McElroy - Psychiatric Annals, 1993 - journals.healio.com
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Lithium: still a major option in the management of bipolar disorder

RW Licht - CNS neuroscience & therapeutics, 2012 - Wiley Online Library
Still after more than 50 years, lithium is a major treatment of bipolar disorder, even though it
has not been promoted by the pharmaceutical industry over the last decades. In recent years …