[HTML][HTML] The role of the hippocampus in approach-avoidance conflict decision-making: evidence from rodent and human studies

R Ito, ACH Lee - Behavioural brain research, 2016 - Elsevier
The hippocampus (HPC) has been traditionally considered to subserve mnemonic
processing and spatial cognition. Over the past decade, however, there has been increasing …

The ventral hippocampus, but not the dorsal hippocampus is critical for learned approach‐avoidance decision making

A Schumacher, E Vlassov, R Ito - Hippocampus, 2016 - Wiley Online Library
The resolution of an approach‐avoidance conflict induced by ambivalent information
involves the appraisal of the incentive value of the outcomes and associated stimuli to …

Examining the role of the human hippocampus in approach–avoidance decision making using a novel conflict paradigm and multivariate functional magnetic …

EB O'Neil, RN Newsome, IHN Li… - Journal of …, 2015 - Soc Neuroscience
Rodent models of anxiety have implicated the ventral hippocampus in approach–avoidance
conflict processing. Few studies have, however, examined whether the human hippocampus …

Ventral hippocampal CA1 and CA3 differentially mediate learned approach-avoidance conflict processing

A Schumacher, FR Villaruel, A Ussling, S Riaz… - Current Biology, 2018 - cell.com
Approach-avoidance conflict arises when an animal encounters a stimulus that is associated
simultaneously with positive and negative valences [1]. The effective resolution of approach …

Arbitration of approach-avoidance conflict by ventral hippocampus

KG Bryant, JM Barker - Frontiers in neuroscience, 2020 - frontiersin.org
When environmental cues or stimuli that represent both rewarding and aversive outcomes
are presented, complex computations must be made in order to determine whether …

Disentangling hippocampal and amygdala contribution to human anxiety-like behavior

DR Bach, M Hoffmann, C Finke… - Journal of …, 2019 - Soc Neuroscience
Anxiety comprises a suite of behaviors to deal with potential threat and is often modeled in
approach–avoidance conflict tasks. Collectively, these tests constitute a predominant …

[HTML][HTML] Human hippocampus arbitrates approach-avoidance conflict

DR Bach, M Guitart-Masip, PA Packard, J Miró, M Falip… - Current Biology, 2014 - cell.com
Animal models of human anxiety often invoke a conflict between approach and avoidance
[1, 2]. In these, a key behavioral assay comprises passive avoidance of potential threat and …

A role for dorsal and ventral hippocampus in inter-temporal choice cost-benefit decision making.

SB McHugh, TG Campbell, AM Taylor… - Behavioral …, 2008 - psycnet.apa.org
Previous studies suggest a preferential role for dorsal hippocampus (dHPC) in spatial
memory tasks, whereas ventral hippocampus (vHPC) has been implicated in aspects of fear …

Neural substrates of approach‐avoidance conflict decision‐making

RL Aupperle, AJ Melrose, A Francisco… - Human brain …, 2015 - Wiley Online Library
Animal approach‐avoidance conflict paradigms have been used extensively to
operationalize anxiety, quantify the effects of anxiolytic agents, and probe the neural basis of …

The neural basis of approach-avoidance conflict: a model based analysis

S Zorowitz, AP Rockhill, KK Ellard, KE Link… - Eneuro, 2019 - eneuro.org
Abstract Approach-avoidance conflict arises when the drives to pursue reward and avoid
harm are incompatible. Previous neuroimaging studies of approach-avoidance conflict have …