Genome‐editing therapeutics are poised to treat human diseases. As we enter clinical trials
with the most promising CRISPR‐Cas9 and CRISPR‐Cas12a (Cpf1) modalities, the risks …

Clustered regularly interspaced short palindromic repeats (CRISPR) form the adaptive
immune system in archaea and bacteria and have been modified for genome engineering in …

Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 is a genome-
editing technology, that utilizes archaeal and bacterial Cas9 nucleases to introduce double …

The repurposing of the CRISPR/Cas microbial adaptive immune system for gene editing has
resulted in an exponential rise in new technologies and promising approaches for treating …

Even though chemotherapy and immunotherapy emerged to limit continual and unregulated
proliferation of cancer cells, currently available therapeutic agents are associated with high …

The famed physicist-turned-biologist, Max Delbrück, once remarked that, for physicists,“the
field of bacterial viruses is a fine playground for serious children who ask ambitious …

Owing to its easy-to-use and multiplexing nature, the genome editing tool CRISPR-Cas9
(clustered regularly interspaced short palindromic repeats (CRISPR) associated nuclease 9) …

CRISPR/Cas9 is an effective gene editing tool with broad applications for the prevention or
treatment of numerous diseases. It depends on CRISPR (clustered regularly interspaced …

A series of recent discoveries harnessing the adaptive immune system of prokaryotes to
perform targeted genome editing is having a transformative influence across the biological …

Translational medicine aims to improve human health by exploring potential treatment
methods developed during basic scientific research and applying them to the treatment of …