Bacterial resistance to antibiotics is a growing phenomenon in the world. Considering the
relevance of antimicrobials for population and the reduction in the registration of new …

Linezolid is a synthetic antimicrobial agent belonging to the oxazolidinone class. Since its
approval in the year 2000 until now, linezolid remains the main representative drug for the …

A liquid chromatographic (LC) method and a UV spectrophotometric method were
developed and validated for quantitative determination of linezolid in tablets and injection …

A simple high‐performance liquid chromatographic (HPLC) method was developed and
validated for rapid quantification of linezolid in human plasma. Protein precipitation using a …

A high-performance liquid chromatographic method for the determination of linezolid in
human plasma was developed and validated. After precipitation of plasma proteins with …

A simple, selective, linear, precise and accurate RP-HPLC method was developed and
validated for rapid assay of LINEZOLID. Isocratic elution at a flow rate of 1.2 ml/min was …

Background: Linezolid serum concentrations have been shown to be highly variable in
critically ill patients with often sub-therapeutic drug levels regarding minimal inhibitory …

An HPLC–UV method was developed for assay of linezolid in dog, rat, mouse, and rabbit
plasma. Linezolid and the internal standard were extracted on a solid phase cartridge (SPE) …

Simple, precise and sensitive methods have been used for the determination of linezolid
and its alkaline induced degradation product and in pharmaceutical dosage form. The first …

A simple, high-throughput reversed-phase high performance liquid chromatography method
with mass spectrometric detection (LC/MS/MS) was developed and validated for the …