The continuous degradation and synthesis of prokaryotic mRNAs not only give rise to the
metabolic changes that are required as cells grow and divide but also rapid adaptation to …

RNA processing and degradation are key processes in the control of transcript accumulation
and thus in the control of gene expression. In Escherichia coli, the underlying mechanisms …

The best characterized pathway for the initiation of mRNA degradation in Escherichia coli
involves the removal of the 5′‐terminal pyrophosphate to generate a monophosphate …

Instability is a fundamental property of mRNA that is necessary for the regulation of gene
expression. In E. coli, the turnover of mRNA involves multiple, redundant pathways involving …

Messenger RNA processing and decay is a key mechanism to control gene expression at
the post-transcriptional level in response to ever-changing environmental conditions. In this …

RNA degradation is a major process controlling RNA levels and plays a central role in cell
metabolism. From the labile messenger RNA to the more stable noncoding RNAs (mostly …

The amount of a messenger RNA available for protein synthesis depends on the efficiency
of its transcription and stability. The mechanisms of degradation that determine the stability …

mRNA degradation is an important mechanism for controlling gene expression in bacterial
cells. This process involves the orderly action of a battery of cellular endonucleases and …

Messenger RNA decay plays an important role in prokaryotic gene expression. The
disparate stabilities of bacterial messages in vivo are a consequence of their differential …

RNase E contains a large non‐catalytic region that binds RNA and the protein components
of the Escherichia coli RNA degradosome. The rne gene was replaced with alleles encoding …