Significant research efforts have been undertaken during the last decades to treat
musculoskeletal disorders and improve patient's mobility and quality of life. The goal is the …

At present, it is well known that populations of human bone marrow stromal cells (HBMSCs)
can differentiate into osteoblasts and produce bone. However, the amount of cells with …

Background aims Advances in bone tissue engineering with mesenchymal stromal cells
(MSC) as an alternative to conventional orthopedic procedures has opened new horizons …

Marrow stromal cells (MSCs) are ideally suited for tissue engineered bone grafts since they
have the potential to regenerate bone, but may also maintain the homeostasis of the …

An overall decline in the availability of osteogenic precursor cells and growth factors in the
bone marrow microenvironment have been associated with impaired bone formation and …

Bone marrow contains a population of rare progenitor cells capable of differentiating into
bone, cartilage, muscle, tendon, and other connective tissues. These cells, referred to as …

In the context of clinical applications of bone regeneration, cell seeding into scaffolds needs
to be safe and easy. Moreover, cell density also plays a crucial role in the development of …

The treatment of severe musculoskeletal injuries, such as loss of bone tissue and
consolidation disorders, requires bone transplantation, and the success of this bone …

Introduction Repair of large bone defects remains a significant clinical challenge. Bone
marrow stromal cells (BMSCs), a subset of which is known as bone marrow-derived …

Bone marrow‐derived stromal cells (BMSCs) contain mesenchymal stem cells that are
capable of forming various mesenchymal tissues. We hypothesized that BMSCs and β …