The locus coeruleus (LC), a small brainstem nucleus, is the primary source of the
neuromodulator norepinephrine (NE) in the brain. The LC receives input from widespread …

The locus coeruleus (LC) is a seemingly singular and compact neuromodulatory nucleus
that is a prominent component of disparate theories of brain function due to its broad …

The release of the neurotransmitter norepinephrine throughout the mammalian brain is
important for modulating attention, arousal, and cognition during many behaviors …

The brainstem nucleus locus coeruleus (LC) is the primary source of norepinephrine (NE) to
the mammalian neocortex. It is believed to operate as a homogeneous syncytium of …

Noradrenaline modulates global brain states and diverse behaviors through what is
traditionally believed to be a homogeneous cell population in the brainstem locus coeruleus …

Ascending neuromodulatory projections from the locus coeruleus (LC) affect cortical neural
networks via the release of norepinephrine (NE). However, the exact nature of these …

Historically, the locus coeruleus–norepinephrine (LC‐NE) system has been implicated in
arousal, but recent findings suggest that this system plays a more complex and specific role …

Many studies in intact animals have shown that locally applied or synaptically released
norepinephrine (NE) can enhance individual neuron and neural network responses to …

Historically, the locus coeruleus-norepinephrine (LC-NE) system has been implicated in
arousal, but recent findings suggest that this system plays a more complex and specific role …

Cognition fluctuates over relatively faster and slower timescales. This is enabled by dynamic
interactions among cortical neurons over similarly diverse temporal and spatial scales. Fast …