The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

Compared to conventional treatments, gene therapy offers a variety of advantages for
cancer treatment including high potency and specificity, low off-target toxicity, and delivery of …

Exosomes are biological membrane vesicles measuring 30 to 100nm. They contain an
abundance of small molecules like tetraspanins, receptors for targeting and adhesion, lipids …

Cancer is a genetic disease originating from the accumulation of gene mutations in a
cellular subpopulation. Although many therapeutic approaches have been developed to …

Background Lack of effective tumor-specific delivery systems remains an unmet clinical
challenge for successful translation of innovative therapies, such as, therapeutic …

Exosomes are a subtype of membrane vesicle released from the endocytic compartment of
live cells. They play an important role in endogenous cell-to-cell communication. Previously …

Drug resistance, difficulty in specific targeting and self-renewal properties of cancer stem
cells (CSCs) all contribute to cancer treatment failure and relapse. CSCs have been …

Gene therapy has been receiving widespread attention due to its unique advantage in
regulating the expression of specific target genes. In the field of cancer gene therapy …

The emergence of nanotechnology applied to medicine has revolutionized the treatment of
human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs …

Simple Summary Nucleic acid drugs provide novel therapeutic modalities with
characteristics that differ from those of small molecules and antibodies. In this review, I focus …