Immunogenic cell death in cancer therapy

G Kroemer, L Galluzzi, O Kepp… - Annual review of …, 2013 - annualreviews.org
Depending on the initiating stimulus, cancer cell death can be immunogenic or
nonimmunogenic. Immunogenic cell death (ICD) involves changes in the composition of the …

Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy

O Kepp, L Galluzzi, I Martins, F Schlemmer… - Cancer and Metastasis …, 2011 - Springer
The success of some chemo-and radiotherapeutic regimens relies on the induction of
immunogenic tumor cell death and on the induction of an anticancer immune response …

[HTML][HTML] Cytokines in immunogenic cell death: applications for cancer immunotherapy

A Showalter, A Limaye, JL Oyer, R Igarashi… - Cytokine, 2017 - Elsevier
Despite advances in treatments like chemotherapy and radiotherapy, metastatic cancer
remains a leading cause of death for cancer patients. While many chemotherapeutic agents …

An overview on immunogenic cell death in cancer biology and therapy

MC Rodrigues, JAV Morais, R Ganassin, GRT Oliveira… - Pharmaceutics, 2022 - mdpi.com
Immunogenic cell death (ICD) is a modality of regulated cell death that is sufficient to
promote an adaptive immune response against antigens of the dying cell in an …

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

I Vanmeerbeek, J Sprooten, D De Ruysscher… - …, 2020 - Taylor & Francis
The term 'immunogenic cell death'(ICD) denotes an immunologically unique type of
regulated cell death that enables, rather than suppresses, T cell-driven immune responses …

Trial watch: chemotherapy-induced immunogenic cell death in oncology

J Sprooten, RS Laureano, I Vanmeerbeek… - …, 2023 - Taylor & Francis
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell
death that activates, rather than suppresses, innate and adaptive immune responses. Such …

Immunogenic cell death in cancer: concept and therapeutic implications

L Galluzzi, O Kepp, E Hett, G Kroemer… - Journal of Translational …, 2023 - Springer
Mammalian cells responding to specific perturbations of homeostasis can undergo a
regulated variant of cell death that elicits adaptive immune responses. As immunogenic cell …

[HTML][HTML] Immunogenic cell death inducers as anticancer agents

O Kepp, L Senovilla, G Kroemer - Oncotarget, 2014 - ncbi.nlm.nih.gov
It has been widely thought that the occasional success of anticancer chemotherapies is
mediated by direct, efficient cytostatic or (better) cytotoxic effects of the antineoplastic agent …

Targeting immunogenic cell death in cancer

A Ahmed, SWG Tait - Molecular oncology, 2020 - Wiley Online Library
Immunogenic cell death (ICD) is a type of cancer cell death triggered by certain
chemotherapeutic drugs, oncolytic viruses, physicochemical therapies, photodynamic …

Trial watch: immunogenic cell death induction by anticancer chemotherapeutics

AD Garg, S More, N Rufo, O Mece, ML Sassano… - …, 2017 - Taylor & Francis
The expression “immunogenic cell death”(ICD) refers to a functionally unique form of cell
death that facilitates (instead of suppressing) a T cell-dependent immune response specific …