Background Because of the increasing life expectancy in our society, aging-related
neurodegenerative disorders are one of the main issues in global health. Most of these …

Extracellular vesicles (EVs) are nanosized vesicles released by almost all body tissues,
representing important mediators of cellular communication, and are thus promising …

Identifying biomarkers is essential for early diagnosis of neurodegenerative diseases (NDs).
Large (LEVs) and small extracellular vesicles (SEVs) are extracellular vesicles (EVs) of …

Protein and miRNA enrichment within extracellular vesicles (EVs) isolated from patients with
Alzheimer's disease (AD) has been shown to have putative diagnostic value. However …

INTRODUCTION Brain cell–derived small extracellular vesicles (sEVs) in blood offer unique
cellular and molecular information related to the onset and progression of Alzheimer's …

Small extracellular vesicles (EVs) are able to pass from the central nervous system (CNS)
into peripheral blood and contain molecule markers of their parental origin. The aim of our …

Objectives There is a lack of effective biomarkers for neurodegenerative diseases (NDs)
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Alzheimer's disease (AD) is a progressive neurodegenerative brain pathology and the most
common form of dementia. Evidence suggests that extracellular vesicles (EVs) containing …

Alzheimer's disease (AD) is one of the most severe neurodegenerative diseases observed
in the elderly population. Although the hallmarks of AD have been identified, the methods for …

Alzheimer's disease is a progressive neurodegenerative disorder, with the strongest disease-
associated changes observed at clinical or end-stage disease. Transcriptomic deregulation …