BOTOX® counteracts the innate anxiety-related behaviours in correlation with increased activities of key antioxidant enzymes in the hippocampus of ageing …

A Yesudhas, RK Radhakrishnan, A Sukesh… - Biochemical and …, 2021 - Elsevier
Cholinergic crisis and oxidative stress in the hippocampus of the brain have been known to
induce anxiety disorders upon ageing. BOTOX® is a widely used therapeutic form of …

Intramuscular injection of BOTOX® boosts learning and memory in adult mice in association with enriched circulation of platelets and enhanced density of pyramidal …

A Yesudhas, SA Roshan, RK Radhakrishnan… - Neurochemical …, 2020 - Springer
BOTOX® is a therapeutic form of botulinum neurotoxin. It acts by blocking the release of
acetylcholine (ACh) from the synaptic vesicles at the neuromuscular junctions, thereby …

Moderate treadmill exercise prevents oxidative stress-induced anxiety-like behavior in rats

S Salim, N Sarraj, M Taneja, K Saha… - Behavioural brain …, 2010 - Elsevier
Recent work has suggested correlation of oxidative stress with anxiety-like behavior. There
also is evidence for anxiolytic effects of physical exercise. However, a direct role of oxidative …

Rivastigmine ameliorates botulinum-induced hippocampal damage and spatial memory impairment in male rats

K Mehri, ZZ Oskuye, E Nassireslami, E Karami… - Neurotoxicology, 2023 - Elsevier
Botulinum toxin (Botox) is widely used in beauty industry and its long-term consequences
can be a matter of concern. The hippocampal cholinergic system plays a significant role in …

Ocimum basilicum improve chronic stress-induced neurodegenerative changes in mice hippocampus

NN Ayuob, MGA El Wahab, SS Ali… - Metabolic brain …, 2018 - Springer
Abstract Alzheimer's disease (AD), one of the progressive neurodegenerative diseases
might be associated with exposure to stress and altered living conditions. This study aimed …

β-Carotene: a natural compound improves cognitive impairment and oxidative stress in a mouse model of streptozotocin-induced Alzheimer's disease

S Hira, U Saleem, F Anwar, MF Sohail, Z Raza… - Biomolecules, 2019 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a cascade of
changes in cognitive, behavioral, and social activities. Several areas of the brain are …

Relationship between oxidative stress and anxiety: emerging role of antioxidants within therapeutic or preventive approaches

J Bouayed - Anxiety disorders, 2011 - books.google.com
Oxidative stress (OS) represents a loss of balance in oxidation-reduction reactions (redox
state). It is characterized by the reduced ability of the antioxidant defense system to …

Oxidant/antioxidant effects of chronic exposure to predator odor in prefrontal cortex, amygdala, and hypothalamus

GE Mejia-Carmona, KL Gosselink… - Molecular and cellular …, 2015 - Springer
The incidence of anxiety-related diseases is increasing these days, hence there is a need to
understand the mechanisms that underlie its nature and consequences. It is known that …

Botox for the brain: enhancement of cognition, mood and pro-social behavior and blunting of unwanted memories

R De Jongh, I Bolt, M Schermer, B Olivier - Neuroscience & Biobehavioral …, 2008 - Elsevier
It has been suggested that the recent rapid developments in the fields of neuroscience and
psychopharmacology have increased the possibilities for pharmacological enhancement of …

[HTML][HTML] Olfactory bulbectomy in mice triggers transient and long-lasting behavioral impairments and biochemical hippocampal disturbances

RF de Almeida, M Ganzella, DG Machado… - Progress in Neuro …, 2017 - Elsevier
Major depressive disorder (MDD) is a neuropsychiatric disease that is associated with
profound disturbances in affected individuals. Elucidating the pathophysiology of MDD has …