Fatty acid transport and signaling: mechanisms and physiological implications
D Samovski, M Jacome-Sosa… - Annual review of …, 2023 - annualreviews.org
Long-chain fatty acids (FAs) are components of plasma membranes and an efficient fuel
source and also serve as metabolic regulators through FA signaling mediated by membrane …
source and also serve as metabolic regulators through FA signaling mediated by membrane …
[HTML][HTML] Cellular uptake, metabolism and sensing of long-chain fatty acids
Q He, Y Chen, Z Wang, H He, P Yu - Frontiers in Bioscience …, 2023 - imrpress.com
Fatty acids (FAs) are critical nutrients that regulate an organism's health and development in
mammal. Long-chain fatty acids (LCFAs) can be divided into saturated and unsaturated fatty …
mammal. Long-chain fatty acids (LCFAs) can be divided into saturated and unsaturated fatty …
[HTML][HTML] Free fatty acid receptors in health and disease
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
Cellular fatty acid uptake: a pathway under construction
X Su, NA Abumrad - Trends in Endocrinology & Metabolism, 2009 - cell.com
Membrane uptake of long-chain fatty acids (FAs) is the first step in cellular FA utilization and
a point of metabolic regulation. CD36 facilitates a major fraction of FA uptake by key tissues …
a point of metabolic regulation. CD36 facilitates a major fraction of FA uptake by key tissues …
Short chain fatty acids and their receptors: new metabolic targets
BT Layden, AR Angueira, M Brodsky, V Durai… - Translational …, 2013 - Elsevier
Fatty acids are carboxylic acids with aliphatic tails of different lengths, where short chain fatty
acids (SCFAs) typically refer to carboxylic acids with aliphatic tails less than 6 carbons. In …
acids (SCFAs) typically refer to carboxylic acids with aliphatic tails less than 6 carbons. In …
Free fatty acid receptors (FFARs) in adipose: physiological role and therapeutic outlook
S Al Mahri, SS Malik, M Al Ibrahim, E Haji, G Dairi… - Cells, 2022 - mdpi.com
Fatty acids (FFAs) are important biological molecules that serve as a major energy source
and are key components of biological membranes. In addition, FFAs play important roles in …
and are key components of biological membranes. In addition, FFAs play important roles in …
[HTML][HTML] Intestinal CD36 and other key proteins of lipid utilization: role in absorption and gut homeostasis
V Cifarelli, NA Abumrad - Comprehensive Physiology, 2018 - ncbi.nlm.nih.gov
Several proteins have been implicated in fatty acid (FA) transport by enterocytes including
the scavenger receptor CD36 (SR-B2), the scavenger receptor B1 (SR-B1) a member of the …
the scavenger receptor CD36 (SR-B2), the scavenger receptor B1 (SR-B1) a member of the …
Role of free fatty acid receptors in the regulation of energy metabolism
Free fatty acids (FFAs) are energy-generating nutrients that act as signaling molecules in
various cellular processes. Several orphan G protein-coupled receptors (GPCRs) that act as …
various cellular processes. Several orphan G protein-coupled receptors (GPCRs) that act as …
Free fatty acid receptors as therapeutic targets for the treatment of diabetes
A Ichimura, S Hasegawa, M Kasubuchi… - Frontiers in …, 2014 - frontiersin.org
Nutrition regulates energy balance; however, dysfunction of energy balance can cause
metabolic disorders, such as obesity and diabetes. Fatty acids are an essential energy …
metabolic disorders, such as obesity and diabetes. Fatty acids are an essential energy …
Distinct Phosphorylation Clusters Determine the Signaling Outcome of Free Fatty Acid Receptor 4/G Protein–Coupled Receptor 120
R Prihandoko, E Alvarez-Curto, BD Hudson… - Molecular …, 2016 - ASPET
It is established that long-chain free fatty acids including ω-3 fatty acids mediate an array of
biologic responses through members of the free fatty acid (FFA) receptor family, which …
biologic responses through members of the free fatty acid (FFA) receptor family, which …