Intervertebral disc (IVD) degeneration is a major cause of low back pain, a prevalent and
chronic condition that has a striking effect on quality of life. Currently, no approved …

Low back pain (LBP), frequently associated with intervertebral disc (IVD) degeneration, is a
major public health concern. LBP is currently managed by pharmacological treatments and …

Intervertebral disc (IVD) degeneration is frequently associated with low back and neck pain,
which accounts for disability worldwide. Despite the known outcomes of the IVD …

Intervertebral disc degeneration is strongly associated with chronic low back pain, a leading
cause of disability worldwide. Current back pain treatment approaches (both surgical and …

Intervertebral disc (IVD) degeneration is a major cause of pain and disability; yet therapeutic
options are limited and treatment often remains unsatisfactory. In recent years, research …

Intervertebral disc (IVD) degeneration is associated with low back pain. In IVDs, a high
mechanical load, high osmotic pressure and hypoxic conditions create a hostile …

Intervertebral disc degeneration is a primary cause of low back pain and has a high societal
cost. Research on cell-based therapies for intervertebral disc disease is emerging, along …

Study Design: Systematic review. Objective: To review, critically appraise, and synthesize
evidence on use of cell therapy for intervertebral disc repair. Methods: A systematic search …

Disc degeneration is the most common cause of back pain in adults and has enormous
socioeconomic implications. Conservative management is ineffective in most cases, and …

Spinal conditions related to intervertebral disc (IVD) degeneration cost billions of dollars in
the US annually. Despite the prevalence and soaring cost, there is no specific treatment that …