FcεRIα gene –18483A>C polymorphism affects transcriptional activity through YY1 binding
DP Potaczek, K Maeda, QH Wang, N Nakano… - Immunogenetics, 2009 - Springer
Three frequent genetic polymorphisms in the human high-affinity IgE receptor α-subunit
(FcεRIα) were shown to be associated with allergic disorders and/or total serum IgE levels in …
(FcεRIα) were shown to be associated with allergic disorders and/or total serum IgE levels in …
The α‐chain of high‐affinity receptor for IgE (FcɛRIα) gene polymorphisms and serum IgE levels
DP Potaczek, M Sanak, L Mastalerz, M Setkowicz… - Allergy, 2006 - Wiley Online Library
Background: The high‐affinity receptor for immunoglobulin‐E (IgE)(FcɛRI) plays a major
role in the pathogenesis of allergy, but there are only two published studies on its α subunit …
role in the pathogenesis of allergy, but there are only two published studies on its α subunit …
Polymorphisms in the FcεRIβ promoter region affecting transcription activity: a possible promoter-dependent mechanism for association between FcεRIβ and atopy
C Nishiyama, Y Akizawa, M Nishiyama… - The Journal of …, 2004 - journals.aai.org
The β subunit of the high-affinity IgE receptor (FcεRI) plays an important role in IgE-mediated
allergic reactions as an amplifier for cell surface expression and signal transduction of FcεRI …
allergic reactions as an amplifier for cell surface expression and signal transduction of FcεRI …
Genetic Variability of the High-affinity IgE Receptor α Subunit (Fc ε RI α) is Related to Total Serum IgE levels in Allergic Subjects
M Sanak, DP Potaczek… - Allergology …, 2007 - Elsevier
Known susceptibility genes to atopy and asthma have been identified by linkage or
associations with clinical phenotypes, including total serum IgE levels. IgE-mediated …
associations with clinical phenotypes, including total serum IgE levels. IgE-mediated …
Allergy-associated polymorphisms of the FcεRIβ subunit do not impact its two amplification functions
E Donnadieu, WO Cookson, MH Jouvin… - The Journal of …, 2000 - journals.aai.org
Two variants of the β-chain of the high affinity IgE receptor FcεRI, I181L-V183L and E237G,
have been found associated with allergy. We have previously shown that the β-chain plays …
have been found associated with allergy. We have previously shown that the β-chain plays …
Genetic variability of the high-affinity IgE receptor α-subunit (FcεRIα)
DP Potaczek, C Nishiyama, M Sanak, A Szczeklik… - Immunologic …, 2009 - Springer
Our knowledge on the variability of FCER1A gene encoding for α-subunit of the high-affinity
immunoglobulin E receptor (FcεRI) that plays a central role in the pathogenesis of allergy …
immunoglobulin E receptor (FcεRI) that plays a central role in the pathogenesis of allergy …
The E237G polymorphism of the high-affinity IgE receptor β chain and asthma
Z Xiaozhu, Z Weidong, Q Diwen, S Andrew… - Annals of Allergy …, 2004 - Elsevier
BACKGROUND: The β chain of high-affinity IgE receptor (FcɛRI β) has been proposed as a
candidate gene for asthma and atopic diseases. OBJECTIVES: To determine the prevalence …
candidate gene for asthma and atopic diseases. OBJECTIVES: To determine the prevalence …
A novel− 66T/C polymorphism in FcεRI α-chain promoter affecting the transcription activity: possible relationship to allergic diseases
M Hasegawa, C Nishiyama, M Nishiyama… - The Journal of …, 2003 - journals.aai.org
We found a novel polymorphism,− 66T/C, in the promoter region of human FcεRIα, the
specific component of the high affinity receptor for IgE (FcεRI), which is essential for the cell …
specific component of the high affinity receptor for IgE (FcεRI), which is essential for the cell …
A new variant of the β subunit of the high-affinity receptor for immunoglobulin E (FcεRI-β E237G): associations with measures of atopy and bronchial hyper …
MR Hill, W Cookson - Human Molecular Genetics, 1996 - academic.oup.com
The high affinity receptor for IgE (FcεRI) has a central role in mast cell degranulation and IgE
mediated allergy. A systematic search through the coding regions of the beta subunit of …
mediated allergy. A systematic search through the coding regions of the beta subunit of …
A comparative search for human FcεRIα gene (FCER1A) 3′-UTR polymorphisms in Japanese and Polish populations
DP Potaczek, M Kamijo, M Hara, K Okumura… - Molecular biology …, 2012 - Springer
The high affinity immunoglobulin E (IgE) receptor (FcεRI) plays a key role in the
pathogenesis of atopy and allergic disorders. Several polymorphisms located in 5′-flanking …
pathogenesis of atopy and allergic disorders. Several polymorphisms located in 5′-flanking …