Introduction The COVID-19 pandemic has revealed an immense, unmet and international
need for available ventilators. Both clinical and engineering groups around the globe have …

Background The COVID-19 pandemic revealed a substantial and unmet need for low-cost,
easily accessible mechanical ventilation strategies for use in medical resource-challenged …

Respiratory failure complicates most critically ill patients with COVID-19 and is characterized
by heterogeneous pulmonary parenchymal involvement, profound hypoxemia and …

Resource-scarce regions with serious COVID-19 outbreaks do not have enough ventilators
to support critically ill patients, and these shortages are especially devastating in developing …

We present a low-cost clinically viable ventilator design, AmbuBox, using a controllable
pneumatic enclosure and standard manual resuscitators that are readily available …

The COVID‐19 pandemic has produced critical shortages of ventilators worldwide. There is
an unmet need for rapidly deployable, emergency‐use ventilators with sufficient functionality …

For the past 50 years, positive pressure ventilation has been a cornerstone of treatment for
respiratory failure. Consensus surrounding the epidemiology of respiratory failure has …

Background The manufacturing of any standard mechanical ventilator cannot rapidly be
upscaled to several thousand units per week, largely due to supply chain limitations. The …

The novel coronavirus disease 2019 (COVID-19) created a shortage of mechanical
ventilators in the healthcare sector, resulting in rationed distribution, ethical dilemmas, and …

Abstract Coronavirus Disease 2019 (COVID-19) threatens to overwhelm our medical
infrastructure at the regional level causing spikes in mortality rates because of shortages of …