High-throughput sequencing technology is rapidly improving in quality, speed and cost. It is
therefore becoming more widely used to study whole communities of prokaryotes in many …

Advances in high-throughput sequencing (HTS) have fostered rapid developments in the
field of microbiome research, and massive microbiome datasets are now being generated …

Microbial community profiling by barcoded 16S rRNA gene amplicon sequencing currently
has many applications in microbial ecology. The low costs of the parallel sequencing of …

Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

Sequence-based approaches to study microbiomes, such as 16S rRNA gene sequencing
and metagenomics, are uncovering associations between microbial taxa and a myriad of …

The human microbiome has emerged as a major player in regulating human health and
disease. Translational studies of the microbiome have the potential to indicate clinical …

There is increasing interest in employing shotgun sequencing, rather than amplicon
sequencing, to analyze microbiome samples. Typical projects may involve hundreds of …

Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …

The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the …

Background The study of microbiomes using whole-metagenome shotgun sequencing
enables the analysis of uncultivated microbial populations that may have important roles in …