Designing biological systems: systems engineering meets synthetic biology

S Rollié, M Mangold, K Sundmacher - Chemical Engineering Science, 2012 - Elsevier
Synthetic Biology offers qualitatively new perspectives on the benefits of industrially
harnessed biological processes. The ability to modify and reprogramme natural biology …

Computational design approaches and tools for synthetic biology

JT MacDonald, C Barnes, RI Kitney… - Integrative …, 2011 - academic.oup.com
A proliferation of new computational methods and software tools for synthetic biology design
has emerged in recent years but the field has not yet reached the stage where the design …

Biology by design: from top to bottom and back

BR Fritz, LE Timmerman, NM Daringer… - BioMed Research …, 2010 - Wiley Online Library
Synthetic biology is a nascent technical discipline that seeks to enable the design and
construction of novel biological systems to meet pressing societal needs. However …

Engineering life: A review of synthetic biology

MM Hanczyc - Artificial life, 2020 - ieeexplore.ieee.org
Synthetic biology is a field of scientific research that applies engineering principles to living
organisms and living systems. It is a field that is increasing in scope with respect to …

Synthetic biology: new engineering rules for an emerging discipline

E Andrianantoandro, S Basu, DK Karig… - Molecular systems …, 2006 - embopress.org
Synthetic biologists engineer complex artificial biological systems to investigate natural
biological phenomena and for a variety of applications. We outline the basic features of …

Tuning the dials of synthetic biology

JAJ Arpino, EJ Hancock, J Anderson… - …, 2013 - microbiologyresearch.org
Synthetic Biology is the 'Engineering of Biology'–it aims to use a forward-engineering design
cycle based on specifications, modelling, analysis, experimental implementation, testing and …

Developments in the tools and methodologies of synthetic biology

R Kelwick, JT MacDonald, AJ Webb… - … in bioengineering and …, 2014 - frontiersin.org
Synthetic biology is principally concerned with the rational design and engineering of
biologically based parts, devices, or systems. However, biological systems are generally …

Synthetic biology advancing clinical applications

M Folcher, M Fussenegger - Current opinion in chemical biology, 2012 - Elsevier
The 'omics' era, with its identification of genetic and protein components, has combined with
systems biology, which provided insights into network structures, to set the stage for …

Principles of synthetic biology

KL Garner - Essays in biochemistry, 2021 - portlandpress.com
In synthetic biology, biological cells and processes are dismantled and reassembled to
make novel systems that do useful things. Designs are encoded by deoxyribonucleic acid …

[HTML][HTML] Principles for the design of multicellular engineered living systems

O Aydin, AP Passaro, R Raman, SE Spellicy… - APL …, 2022 - pubs.aip.org
Remarkable progress in bioengineering over the past two decades has enabled the
formulation of fundamental design principles for a variety of medical and non-medical …