ABSTRACT Alpha-lactalbumin (α-LA), a small milk calcium-binding globular protein, is
known to possess noticeable anticancer activity, which is determined by the ability of this …

Abstract α-Lactalbumin is a ubiquitous calcium-binding milk protein with a well-
characterized function in regulating the synthesis of lactose. An entirely different activity has …

Background Alpha-lactalbumin (α-LA) is a calcium-bound mammary gland-specific protein
that is found in milk. This protein is a modulator of β1, 4-galactosyltransferase enzyme …

The protein alpha-lactalbumin (α-LA) is present in the milk of nearly all mammals. Here it
has a well-described function of controlling the specificity of a galatosyltransferase towards …

The biological function of α-lactalbumin (α-LA) depends on its conformation. α-LA can adopt
a stable intermediate state induced by heating or pH change. This intermediate state …

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), which was identified in
human breast milk as an alpha-lactalbumin (LA)–oleic acid complex, kills tumor cells …

HAMLET (human α-lactalbumin made lethal to tumor cells) is a tumoricidal complex of apo α-
lactalbumin and oleic acid, formed in casein after low pH treatment of human milk. This study …

Some natural proteins induce tumor-selective apoptosis. α-Lactalbumin (α-LA), a milk
calcium-binding protein, is converted into an antitumor form, called HAMLET/BAMLET, via …

α-Lactalbumin (α-LA) is a small (Mr 14,200), acidic (pI 4–5), Ca2+-binding protein. α-LA is a
regulatory component of lactose synthase enzyme system functioning in the lactating …

The whey protein a-lactalbumin, derived from human milk, has been shown to inhibit
proliferation of mammary epithelial cells and rat kidney cells. We have shown that bovine a …