p38 mitogen-activated protein kinase is not activated in the quadriceps of patients with stable chronic obstructive pulmonary disease

J Riddoch-Contreras, T George… - COPD: Journal of …, 2012 - Taylor & Francis
Quadriceps weakness is associated with a poor prognosis in COPD. Several data suggest
that immobility and muscle wasting may be related through up-regulation of the p38 Mitogen …

Prevalence of quadriceps muscle weakness in patients with COPD and its association with disease severity

S Kharbanda, A Ramakrishna… - International journal of …, 2015 - Taylor & Francis
Introduction COPD presents with an array of extra-pulmonary symptoms of which skeletal
muscle dysfunction, particularly of the quadriceps, is well recognized. This contributes to …

The prevalence of quadriceps weakness in COPD and the relationship with disease severity

JM Seymour, MA Spruit, NS Hopkinson… - European …, 2010 - Eur Respiratory Soc
Quadriceps strength relates to exercise capacity and prognosis in chronic obstructive
pulmonary disease (COPD). We wanted to quantify the prevalence of quadriceps weakness …

Abdominal muscle and quadriceps strength in chronic obstructive pulmonary disease

WDC Man, NS Hopkinson, F Harraf, D Nikoletou… - Thorax, 2005 - thorax.bmj.com
Background: Quadriceps muscle weakness is common in chronic obstructive pulmonary
disease (COPD) but is not observed in a small hand muscle (adductor pollicis). Although this …

Quadriceps muscle strength in scoliosis

EB Swallow, E Barreiro, H Gosker… - European respiratory …, 2009 - Eur Respiratory Soc
Quadriceps muscle weakness is an important component of chronic obstructive pulmonary
disease (COPD). We hypothesised that quadriceps weakness would also be a feature of …

Quadriceps wasting and physical inactivity in patients with COPD

D Shrikrishna, M Patel, RJ Tanner… - European …, 2012 - Eur Respiratory Soc
Quadriceps weakness is an important complication of advanced chronic obstructive
pulmonary disease (COPD) but few data exist concerning muscle bulk in early disease. We …

Factors associated with impairment of quadriceps muscle function in Chinese patients with chronic obstructive pulmonary disease

C Ju, R Chen - PloS one, 2014 - journals.plos.org
Background Quadriceps muscle dysfunction is well confirmed in chronic obstructive
pulmonary disease (COPD) and reported to be related to a higher risk of mortality. Factors …

Distal leg muscle function in patients with COPD

P Gagnon, F Maltais, L Bouyer, F Ribeiro… - COPD: Journal of …, 2013 - Taylor & Francis
Quadriceps muscle weakness and increased fatigability are well described in patients with
chronic obstructive pulmonary disease (COPD). Whether these functional alterations also …

MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease

BB Lemire, R Debigaré, A Dubé… - Journal of applied …, 2012 - journals.physiology.org
Muscle atrophy in chronic obstructive pulmonary disease (COPD) is associated with
reduced exercise tolerance, muscle strength, and survival. The molecular mechanisms …

Ischiocrural strength may be a better prognostic marker than quadriceps strength in COPD

E Pleguezuelos, L Guirao, E Moreno, B Samitier… - Lung, 2018 - Springer
It is well known that chronic obstructive pulmonary disease (COPD) patients present with
muscle dysfunction that may not correlate with the degree of severity of airflow obstruction …