Genetic and epigenetic drivers of neuroendocrine tumours (NET)
A Di Domenico, T Wiedmer, I Marinoni… - Endocrine-related …, 2017 - erc.bioscientifica.com
Neuroendocrine tumours (NET) of the gastrointestinal tract and the lung are a rare and
heterogeneous group of tumours. The molecular characterization and the clinical …
heterogeneous group of tumours. The molecular characterization and the clinical …
Genetics and epigenetics of gastroenteropancreatic neuroendocrine neoplasms
A Mafficini, A Scarpa - Endocrine reviews, 2019 - academic.oup.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …
Clinical epigenetics of neuroendocrine tumors: the road ahead
Neuroendocrine tumors, or NETs, are cancer originating in neuroendocrine cells. They are
mostly found in the gastrointestinal tract or lungs. Functional NETs are characterized by …
mostly found in the gastrointestinal tract or lungs. Functional NETs are characterized by …
Multilayered heterogeneity as an intrinsic hallmark of neuroendocrine tumors
Neuroendocrine tumors (NETs) comprise a complex and highly heterogeneous group of
neoplasms that can arise all over the body, originating from neuroendocrine cells. NETs are …
neoplasms that can arise all over the body, originating from neuroendocrine cells. NETs are …
Genomic landscape of pancreatic neuroendocrine tumours: the International Cancer Genome Consortium
A Mafficini, A Scarpa - Journal of Endocrinology, 2018 - joe.bioscientifica.com
Neuroendocrine tumours (NETs) may arise throughout the body and are a highly
heterogeneous, relatively rare class of neoplasms difficult to study also for the lack of …
heterogeneous, relatively rare class of neoplasms difficult to study also for the lack of …
Hallmarks of gastrointestinal neuroendocrine tumours: implications for treatment
A Walenkamp, G Crespo, FF Maya… - Endocrine-related …, 2014 - erc.bioscientifica.com
In the past few years, there have been advances in the treatment of neuroendocrine tumours
(NETs) and improvements in our understanding of NET biology. However, the benefits to …
(NETs) and improvements in our understanding of NET biology. However, the benefits to …
GEP-NETS UPDATE: Genetics of neuroendocrine tumors
J Crona, B Skogseid - European journal of endocrinology, 2016 - academic.oup.com
Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms, arising from
neuroendocrine cells that are dispersed throughout the body. Around 20% of NETs occur in …
neuroendocrine cells that are dispersed throughout the body. Around 20% of NETs occur in …
The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets
Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) form clinically and
genetically heterogeneous malignancies, characterized by distinct prognoses based upon …
genetically heterogeneous malignancies, characterized by distinct prognoses based upon …
Prognostic impact of novel molecular subtypes of small intestinal neuroendocrine tumor
A Karpathakis, H Dibra, C Pipinikas, A Feber… - Clinical Cancer …, 2016 - AACR
Purpose: Small intestinal neuroendocrine tumors (SINET) are the commonest malignancy of
the small intestine; however, underlying pathogenic mechanisms remain poorly …
the small intestine; however, underlying pathogenic mechanisms remain poorly …
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract
H Wu, Z Yu, Y Liu, L Guo, L Teng, L Guo… - Cancer …, 2022 - Wiley Online Library
Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a
disease of grim prognosis with limited therapeutic options. Their molecular characteristics …
disease of grim prognosis with limited therapeutic options. Their molecular characteristics …