[HTML][HTML] Artificial neural network modelling hydrodenticity for optimal design by microfluidics of polymer nanoparticles to apply in magnetic resonance imaging

A Smeraldo, AM Ponsiglione, PA Netti, E Torino - Acta Biomaterialia, 2023 - Elsevier
The engineering of nanoparticles impacts the control of their nano-bio interactions at each
level of the delivery pathway. Therefore, optimal nanoparticle physicochemical properties …

Machine learning instructed microfluidic synthesis of curcumin-loaded liposomes

V Di Francesco, DP Boso, TL Moore, BA Schrefler… - Biomedical …, 2023 - Springer
The association of machine learning (ML) tools with the synthesis of nanoparticles has the
potential to streamline the development of more efficient and effective nanomedicines. The …

Finding key nanoprecipitation variables for achieving uniform polymeric nanoparticles using neurofuzzy logic technology

MO Jara, J Catalan-Figueroa, M Landin… - Drug delivery and …, 2018 - Springer
Nanoprecipitation is a simple and fast method to produce polymeric nanoparticles (Np);
however, most applications require filtration or another separation technique to isolate the …

Prediction of nanoparticle sizes for arbitrary methacrylates using artificial neuronal networks

J Kimmig, T Schuett, A Vollrath, S Zechel… - Advanced …, 2021 - Wiley Online Library
Particle sizes represent one of the key factors influencing the usability and specific targeting
of nanoparticles in medical applications such as vectors for drug or gene therapy. A multi …

Artificial neural network based particle size prediction of polymeric nanoparticles

J Youshia, ME Ali, A Lamprecht - European Journal of Pharmaceutics and …, 2017 - Elsevier
Particle size of nanoparticles and the respective polydispersity are key factors influencing
their biopharmaceutical behavior in a large variety of therapeutic applications. Predicting …

A new microfluidic setup for precise control of the polymer nanoprecipitation process and lipophilic drug encapsulation

N Anton, F Bally, CA Serra, A Ali, Y Arntz, Y Mely… - Soft Matter, 2012 - pubs.rsc.org
A new microfluidic setup with impact-jet micromixers was built up and applied to control the
nanoprecipitation process for generating polymeric nanoparticles and encapsulating a …

Polymeric nanoparticles assembled with microfluidics for drug delivery across the blood-brain barrier

MR Tavares, LR De Menezes… - The European Physical …, 2016 - Springer
The blood-brain barrier (BBB) is a challenge in the treatment of some diseases, since it
prevents many drugs from reaching therapeutic concentrations in the brain. In this context …

Controlled and tunable polymer particles' production using a single microfluidic device

B Amoyav, O Benny - Applied Nanoscience, 2018 - Springer
Microfluidics technology offers a new platform to control liquids under flow in small volumes.
The advantage of using small-scale reactions for droplet generation along with the capacity …

A review of design and fabrication methods for nanoparticle network hydrogels for biomedical, environmental, and industrial applications

MA Campea, MJ Majcher, A Lofts… - Advanced Functional …, 2021 - Wiley Online Library
Nanoparticle network hydrogels (NNHs) in which nanoparticles are used as a key building
block to build the gel network have attracted significant interest given their potential to …

Gaussian processes modeling for the prediction of polymeric nanoparticle formulation design to enhance encapsulation efficiency and therapeutic efficacy

S Dong, H Yu, P Poupart, EA Ho - Drug Delivery and Translational …, 2024 - Springer
Conventional drugs have been facing various drug delivery obstacles, including first-pass
metabolism for oral medications, drug degradation by cellular enzymes, off-target effects …