Importance The use of gabapentinoids in multimodal postoperative analgesia is increasing;
however, when coadministered with opioids, these drugs may potentiate central nervous …

Importance Gabapentin has been increasingly used as part of a multimodal analgesia
regimen to reduce opioid use in perioperative pain management. However, the safety of …

Background: Gabapentinoids are commonly prescribed in perioperative multimodal
analgesia protocols. Despite widespread use, the optimal dose to reduce opioid …

BACKGROUND: Gabapentinoids are widely used in perioperative multimodal analgesic
regimens. The primary aim of this study was to determine whether gabapentin was …

Background Single preoperative gabapentinoid (gabapentin and pregabalin) administration
has been associated with respiratory depression during Phase I anaesthesia recovery. In …

Importance Guidelines recommend using gabapentin to decrease postoperative pain and
opioid use, but significant variation exists in clinical practice. Objective To determine the …

BACKGROUND: Gabapentin and pregabalin have antiallodynic and antihyperalgesic
properties useful for treating neuropathic pain. These properties may also be beneficial in …

Prescription of gabapentin and pregabalin in the perioperative period has become
increasingly common, if not de rigueur. These gabapentinoids have become ubiquitous …

Introduction Overuse of gabapentin and/or opioids occurs in a small percentage of patients
at> 3-fold labeled dosages. Gabapentin may potentiate opioid effects. Objective The aim …

Objectives Effective postoperative pain management is crucial in the care of surgical
patients. Opioids, which are commonly used in managing postoperative pain, have a …