This study aimed to determine whether sulcal morphology differs between middle age (MA)
and older healthy individuals. Furthermore, we sought to determine whether age-related …

Measuring the geometry or morphology of sulcal folds has recently become an important
approach to investigating neuroanatomy. However, relationships between cortical sulci and …

A large number of structural brain studies using magnetic resonance imaging (MRI) have
reported age-related cortical changes and sex difference in brain morphology. Most studies …

The relationship between cognitive functions and brain structure has been of long-standing
research interest. Most previous research has attempted to relate cognition to volumes of …

The relationships between aging and brain morphology have been reported in many
previous structural brain studies. However, the trajectories of successful brain aging in the …

The present study investigated changes in sulcal morphology associated with late-life aging
and mild cognitive impairment (MCI). Participants were 219 community-dwelling 70–90year …

Sulcal morphology has been reported to change with age-related neurological diseases, but
the trajectories of sulcal change in normal ageing in the elderly is still unclear. We …

The age‐related trends of the width and the depth of major cortical sulci were studied in
normal adults. Ninety healthy subjects (47 males, 43 females) age 20–82 years were …

Imaging studies of the human brain indicate that the cortex undergoes anatomic changes
during the aging process. With the ability to study the human brain in vivo using magnetic …

We investigated the changes of sulcal shape (average mean curvature in folded regions and
sulcal depth) in mild cognitive impairment (MCI) and Alzheimer's disease (AD) using …