Background: Gamma-linolenic acid (GLA) is found in animals and plants that play a role in
brain function and metabolism. Objective: This study aimed to investigate the analgesic …

Chlorogenic acid (CGA), one of the most abundant dietary polyphenols, is known to have
various physiological properties. Although CGA is reported to have an antinociceptive effect …

Purpose: Conjugated linoleic acid (CLA) has been suggested to be necessary for human
health, but there is limited research regarding its effect on neuropathic pain (NP). Here, we …

Abstract Treatment of neuropathic pain is far from satisfactory. This study sought evidence of
a neuroprotective effect of alpha-lipoic acid (ALA) to treat neuropathic pain in a chronic …

Chlorogenic acid (CGA) is a natural organic phenolic compound that is found in many
plants, fruits and vegetables. CGA has beneficial bioactivities and strong therapeutic effects …

The present study aimed to evaluate possible antinociceptive effects of chlorogenic acid in
streptozotocin-induced diabetic neuropathic pain in rats. Chlorogenic acid (100 mg/kg) was …

Background Chronic neuropathic pain syndrome is associated with impaired quality of life
and is poorly manageable. Alpha lipoic acid (ALA) is a powerful antioxidant and showed its …

The present study was carried out to investigate on the possible involvement of l‐
arginine/nitric oxide/cyclic guanosine monophosphate (l‐arginine/NO/cGMP) pathway in the …

Background: Green tea is believed to have some health promoting benefits. Among them
anti-inflammatory properties are proposed to cause an analgesic effect. Few studies also …

(–)‐Linalool is a natural compound with anti‐inflammatory and antinociceptive properties.
The antinociceptive action of linalool has been reported in several models of inflammatory …