AGS3, an α (1–3) glucan synthase gene family member of Aspergillus fumigatus, modulates mycelium growth in the lung of experimentally infected mice

D Maubon, S Park, M Tanguy, M Huerre… - Fungal Genetics and …, 2006 - Elsevier
The cell wall of human fungal pathogen Aspergillus fumigatus protects the fungus against
threats from environment and interacts with the host immune system. α (1–3) glucan is the …

Two α(1-3) Glucan Synthases with Different Functions in Aspergillus fumigatus

A Beauvais, D Maubon, S Park, W Morelle… - Applied and …, 2005 - Am Soc Microbiol
ABSTRACT α (1-3) glucan is a main component of the Aspergillus fumigatus cell wall. In
spite of its importance, synthesis of this amorphous polymer has not been investigated to …

Deletion of the α-(1,3)-Glucan Synthase Genes Induces a Restructuring of the Conidial Cell Wall Responsible for the Avirulence of Aspergillus fumigatus

A Beauvais, S Bozza, O Kniemeyer, C Formosa… - PLoS …, 2013 - journals.plos.org
α-(1, 3)-Glucan is a major component of the cell wall of Aspergillus fumigatus, an
opportunistic human fungal pathogen. There are three genes (AGS1, AGS2 and AGS3) …

Deletion of GEL2 encoding for a β(1–3)glucanosyltransferase affects morphogenesis and virulence in Aspergillus fumigatus

I Mouyna, W Morelle, M Vai, M Monod… - Molecular …, 2005 - Wiley Online Library
The first fungal glycosylphosphatidylinositol an‐chored β (1–3) glucanosyltranferase (Gel1p)
has been described in Aspergillus fumigatus and its encoding gene GEL1 identified …

α1, 3 glucans are dispensable in Aspergillus fumigatus

C Henry, JP Latgé, A Beauvais - Eukaryotic cell, 2012 - Am Soc Microbiol
ABSTRACT A triple α1, 3 glucan synthase mutant of Aspergillus fumigatus obtained by
successive deletions of the three α1, 3 glucan synthase genes (AGS1, AGS2, and AGS3) …

Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus*♦

NC Bamford, BD Snarr, FN Gravelat, DJ Little… - Journal of Biological …, 2015 - ASBMB
Aspergillus fumigatus is the most virulent species within the Aspergillus genus and causes
invasive infections with high mortality rates. The exopolysaccharide galactosaminogalactan …

Specific molecular features in the organization and biosynthesis of the cell wall of Aspergillus fumigatus

JP Latgé, I Mouyna, F Tekaia, A Beauvais… - Medical …, 2005 - Taylor & Francis
The cell wall of Aspergillus fumigatus is composed of a branched β1, 3 glucan covalently
bound to chitin, β1, 3, β1, 4 glucans, and galactomannan, that is embedded in an …

Identification and Deletion of Tft1, a Predicted Glycosyltransferase Necessary for Cell Wall β-1,3;1,4-Glucan Synthesis in Aspergillus fumigatus

D Samar, JB Kieler, JS Klutts - PLoS One, 2015 - journals.plos.org
Aspergillus fumigatus is an environmental mold that causes severe, often fatal invasive
infections in immunocompromised patients. The search for new antifungal drug targets is …

The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence

DE Ejzykowicz, MM Cunha, S Rozental… - Molecular …, 2009 - Wiley Online Library
Aspergillus fumigatus causes serious and frequently fatal infections in immunocompromised
patients. To investigate the regulation of virulence of this fungus, we constructed and …

Contribution of Galactofuranose to the Virulence of the Opportunistic Pathogen Aspergillus fumigatus

PS Schmalhorst, S Krappmann, W Vervecken… - Eukaryotic …, 2008 - Am Soc Microbiol
The filamentous fungus Aspergillus fumigatus is responsible for a lethal disease called
invasive aspergillosis that affects immunocompromised patients. This disease, like other …