Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients

CH GeurtsvanKessel, D Geers, KS Schmitz… - Science …, 2022 - science.org
The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …

Diminished neutralization responses towards SARS-CoV-2 Omicron VoC after mRNA or vector-based COVID-19 vaccinations

H Jacobsen, M Strengert, H Maaß, MA Ynga Durand… - Scientific reports, 2022 - nature.com
SARS-CoV-2 variants accumulating immune escape mutations provide a significant risk to
vaccine-induced protection against infection. The novel variant of concern (VoC) Omicron …

Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant

Y Gao, C Cai, A Grifoni, TR Müller, J Niessl… - Nature medicine, 2022 - nature.com
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Omicron (B. 1.1. 529) variant of concern (VOC) has destabilized global efforts to control the …

Different neutralization profiles after primary SARS-CoV-2 Omicron BA. 1 and BA. 2 infections

I Medits, DN Springer, M Graninger, JV Camp… - Frontiers in …, 2022 - frontiersin.org
Background and Methods The SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2) Omicron (B. 1.1. 529) variant is the antigenically most distinct variant to date …

Homologous or heterologous booster of inactivated vaccine reduces SARS-CoV-2 Omicron variant escape from neutralizing antibodies

X Wang, X Zhao, J Song, J Wu, Y Zhu, M Li… - Emerging microbes & …, 2022 - Taylor & Francis
The massive and rapid transmission of SARS-CoV-2 has led to the emergence of several
viral variants of concern (VOCs), with the most recent one, B. 1.1. 529 (Omicron), which …

[HTML][HTML] SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents

P Garcia-Valtanen, CM Hope, MG Masavuli… - Cell Reports …, 2022 - cell.com
Summary Coronavirus disease 2019 (COVID-19) convalescents living in regions with low
vaccination rates rely on post-infection immunity for protection against re-infection with …

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

WF Garcia-Beltran, KJS Denis, A Hoelzemer, EC Lam… - Cell, 2022 - cell.com
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.
1/B. 1.1. 529) harboring up to 36 mutations in spike protein, the target of neutralizing …

SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease

E Barnes, CS Goodyear, M Willicombe, C Gaskell… - Nature medicine, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immune responses and
infection outcomes were evaluated in 2,686 patients with varying immune-suppressive …

mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant

VV Edara, KE Manning, M Ellis, L Lai, KM Moore… - Cell Reports …, 2022 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant
emerged in November 2021 and consists of several mutations within the spike. We use …

Broad neutralization of SARS-CoV-2 variants, including omicron, following breakthrough infection with Delta in COVID-19-vaccinated individuals

T Lechmere, LB Snell, C Graham, J Seow, ZA Shalim… - Mbio, 2022 - Am Soc Microbiol
Numerous studies have shown that a prior SARS-CoV-2 infection can greatly enhance the
antibody response to COVID-19 vaccination, with this so called “hybrid immunity” leading to …