Impact of adolescent intermittent ethanol exposure on interneurons and their surrounding perineuronal nets in adulthood
CA Dannenhoffer, A Gómez‐A… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background Binge alcohol exposure during adolescence results in long‐lasting alterations
in the brain and behavior. For example, adolescent intermittent ethanol (AIE) exposure in …
in the brain and behavior. For example, adolescent intermittent ethanol (AIE) exposure in …
Effects of adolescent intermittent ethanol exposure on cortical perineuronal net and parvalbumin expression in adulthood mediate behavioral inflexibility
EDK Sullivan, CA Dannenhoffer… - Alcohol: Clinical and …, 2024 - Wiley Online Library
Background Alcohol is commonly consumed by adolescents in a binge‐like pattern, which
can lead to long‐lasting cognitive deficits, including reduced behavioral flexibility. We and …
can lead to long‐lasting cognitive deficits, including reduced behavioral flexibility. We and …
Repeated binge drinking increases perineuronal nets in the insular cortex
H Chen, D He, AW Lasek - Alcoholism: Clinical and …, 2015 - Wiley Online Library
Background Alcohol exposure leads to changes in the extracellular matrix (ECM) in the
brain, which profoundly impacts neuronal plasticity. Perineuronal nets (PN s) are specialized …
brain, which profoundly impacts neuronal plasticity. Perineuronal nets (PN s) are specialized …
[HTML][HTML] Diverging effects of adolescent ethanol exposure on tripartite synaptic development across prefrontal cortex subregions
Adolescence is a developmental period that encompasses, but is not limited to, puberty and
continues into early adulthood. During this period, maturation and refinement are observed …
continues into early adulthood. During this period, maturation and refinement are observed …
Persistent alterations of accumbal cholinergic interneurons and cognitive dysfunction after adolescent intermittent ethanol exposure
Adolescent binge drinking renders young drinkers vulnerable to alcohol use disorders in
adulthood; therefore, understanding alcohol-induced brain damage and associated …
adulthood; therefore, understanding alcohol-induced brain damage and associated …
[HTML][HTML] Adolescent intermittent ethanol exposure reduces astrocyte-synaptic proximity in the adult medial prefrontal cortex in rats: Reversal by gabapentin
Alcohol consumption in adolescence causes multiple acute negative changes in neural and
behavioral function that persist well into adulthood and possibly throughout life. The medial …
behavioral function that persist well into adulthood and possibly throughout life. The medial …
Effects of ethanol on persistent activity and up‐states in excitatory and inhibitory neurons in prefrontal cortex
JJ Woodward, MJ Pava - Alcoholism: Clinical and …, 2009 - Wiley Online Library
Background: Elucidating mechanisms that underlie the neural actions of ethanol is critical for
understanding how this drug affects behavior. Increasing evidence suggests that, in addition …
understanding how this drug affects behavior. Increasing evidence suggests that, in addition …
Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood
Background Human adolescence is a crucial stage of neurological development during
which ethanol (EtOH) consumption is often at its highest. Alcohol abuse during adolescence …
which ethanol (EtOH) consumption is often at its highest. Alcohol abuse during adolescence …
Chronic gestational exposure to ethanol leads to enduring aberrances in cortical form and function in the medial prefrontal cortex
AGJ Skorput, HH Yeh - Alcoholism: Clinical and Experimental …, 2016 - Wiley Online Library
Background Exposure to ethanol (EtOH) in utero alters the disposition of tangentially
migrating GABA ergic interneurons in the fetal brain. The medial ganglionic eminence …
migrating GABA ergic interneurons in the fetal brain. The medial ganglionic eminence …
Adolescent alcohol exposure decreases frontostriatal resting‐state functional connectivity in adulthood
Connectivity of the prefrontal cortex (PFC) matures through adolescence, coinciding with
emergence of adult executive function and top‐down inhibitory control over behavior …
emergence of adult executive function and top‐down inhibitory control over behavior …