Our intention is to demystify the MR quantification of hepatic iron (ie, the liver iron
concentration) and give you a step-by-step approach by answering the most pertinent …

Objectives To evaluate the performance and limitations of the R2* and signal intensity ratio
(SIR) methods for quantifying liver iron concentration (LIC) at 3 T. Methods A total of 105 …

Purpose: We compared the calibration of hepatic iron based on R2* relaxometry and liver
biopsy with similar studies that have already been published to investigate the transferability …

Precise, reproducible measurements of liver iron concentration (LIC) are critical for the early
diagnosis, treatment and follow-up of patients with primary or secondary iron overload …

Accumulation of excess iron in the body, or systemic iron overload, results from a variety of
causes. The concentration of iron in the liver is linearly related to the total body iron stores …

Iron overload is a systemic disorder and is either primary (genetic) or secondary (exogenous
iron administration). Primary iron overload is most commonly associated with hereditary …

In recent years, there has been increasing interest in non-invasive iron measurement,
especially of the liver and heart, in patients with iron overload. Serum ferritin still remains an …

PURPOSE: To evaluate the accuracy of magnetic resonance (MR) imaging in the
quantification of hepatic iron concentration. MATERIALS AND METHODS: Between April …

PURPOSE: To identify a magnetic resonance (MR) imaging method sufficiently sensitive
and specific in the estimation of hepatic iron content to obviate liver biopsy. MATERIALS …

Objectives To prospectively evaluate a 3D-multiecho-Dixon sequence with inline calculation
of proton density fat fraction (PDFF) and R2*(qDixon), and an improved version of it (qDixon …