Analytical methodologies for the determination of benzodiazepines in biological samples

K Persona, K Madej, P Knihnicki… - Journal of Pharmaceutical …, 2015 - Elsevier
Benzodiazepine drugs belong to important and most widely used medicaments. They
demonstrate such therapeutic properties as anxiolytic, sedative, somnifacient …

[HTML][HTML] Analytical methods for determination of benzodiazepines. A short review

P Szatkowska, M Koba, P Kośliński, J Wandas… - Open …, 2014 - degruyter.com
Benzodiazepines (BDZs) are generally commonly used as anxiolytic and/or hypnotic drugs
as a ligand of the GABAA-benzodiazepine receptor. Moreover, some of benzodiazepines …

Biopharmacological data and high-performance liquid chromatographic analysis of 1, 4-benzodiazepines in biological fluids: a review

LA Berrueta, B Gallo, F Vicente - Journal of pharmaceutical and biomedical …, 1992 - Elsevier
A review with 123 references on the analysis of 1, 4-benzodiazepines in biological samples
using HPLC is presented. Some important physico-chemical and biopharmacological data …

Chromatography of benzodiazepines

A Sioufi, JP Dubois - Journal of Chromatography B: Biomedical Sciences …, 1990 - Elsevier
An overview of methods for the determination of benzodiazepines in biological media,
based on the application of chromatographic techniques, is presented. A general discussion …

Analytical methods used for the detection and quantification of benzodiazepines

Z Qriouet, Z Qmichou, N Bouchoutrouch… - Journal of analytical …, 2019 - Wiley Online Library
The prescription of psychotropic drugs, especially benzodiazepines (BZDs), occupies a
preponderant place in the management of mental illnesses. Indeed, the BZDs have been …

Rapid analysis of benzodiazepines in whole blood by high-performance liquid chromatography: use of a monolithic column

A Bugey, C Staub - Journal of pharmaceutical and biomedical analysis, 2004 - Elsevier
In a previous work [J. Pharm. Biomed. Anal. 23 (2000) 447] a rapid high-performance liquid
chromatography (HPLC) method, using a monolithic column in HPLC coupled with a diode …

Screening and determination of benzodiazepines in whole blood using solid-phase extraction and gas chromatography/mass spectrometry

H Inoue, Y Maeno, M Iwasa, R Matoba… - Forensic science …, 2000 - Elsevier
Benzodiazepines are one of the most widely prescribed drugs for the treatment of a wide
spectrum of clinical disorders. They are used as anticonvulsants, anxiolytics, hypnotics or …

Overview of the bioanalytical methods used for the determination of benzodiazepines in biological samples and their suitability for emergency toxicological analysis

M Yafout, RA Mouss, H Bouchafra, L Zarayby… - … of Pharmacological and …, 2023 - Elsevier
Benzodiazepines are one of the most widely used classes of drugs around the world. They
are medically used in different therapeutic areas including insomnia, anxiety, epilepsy, and …

Simultaneous determination of benzodiazepines in whole blood or serum by HPLC/DAD with a semi-micro column

A El Mahjoub, C Staub - Journal of pharmaceutical and biomedical …, 2000 - Elsevier
A simple and sensitive high performance liquid chromatographic (HPLC) method using a
semi-micro column, C8 reversed-phase column (3 mm id) and a low flow rate 0.3 ml/min was …

A rapid solid-phase extraction and HPLC/DAD procedure for the simultaneous determination and quantification of different benzodiazepines in serum, blood and post …

F Musshoff, T Daldrup - International Journal of Legal Medicine, 1992 - Springer
A rapid and quantitative method for the determination of benzodiazepines using high-
performance liquid chromatography (HPLC) with diode-array detection (DAD) is reported …