Molecular mimicry and autoimmunity in the time of COVID-19

M Rojas, M Herrán, C Ramírez-Santana… - Journal of …, 2023 - Elsevier
Infectious diseases are commonly implicated as potential initiators of autoimmune diseases
(ADs) and represent the most commonly known factor in the development of autoimmunity in …

[HTML][HTML] From anti-SARS-CoV-2 immune responses to COVID-19 via molecular mimicry

D Kanduc - Antibodies, 2020 - mdpi.com
Aim: To define the autoimmune potential of Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) infection. Methods: Experimentally validated epitopes …

Molecular mimicry, hyperactive immune system, and SARS-COV-2 are three prerequisites of the autoimmune disease triangle following COVID-19 infection

M Vahabi, T Ghazanfari, S Sepehrnia - International Immunopharmacology, 2022 - Elsevier
SARS-CoV-2 infection can produce a variety of clinical manifestations, which are either
directly related to viral tissue damage or indirectly induced by the antiviral immune …

Untangling COVID-19 and autoimmunity: Identification of plausible targets suggests multi organ involvement

M Mohkhedkar, SSK Venigalla, V Janakiraman - Molecular Immunology, 2021 - Elsevier
Underlying mechanisms of multi-organ manifestations and exacerbated inflammation in
COVID-19 are yet to be delineated. The hypothesis of SARS-CoV-2 triggering autoimmunity …

[HTML][HTML] From anti-SARS-CoV-2 immune response to the cytokine storm via molecular mimicry

D Kanduc - Antibodies, 2021 - mdpi.com
The aim of this study was to investigate the role of molecular mimicry in the cytokine storms
associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Human …

[HTML][HTML] Molecular mimicry between SARS-CoV-2 proteins and human self-antigens related with autoimmune Central Nervous System (CNS) disorders

EG Gutman, RA Fernandes, JV Raposo-Vedovi… - Microorganisms, 2023 - mdpi.com
SARS-CoV-2 can trigger autoimmune central nervous system (CNS) diseases in genetically
susceptible individuals, a mechanism poorly understood. Molecular mimicry (MM) has been …

[HTML][HTML] Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity

J Lyons-Weiler - Journal of translational autoimmunity, 2020 - Elsevier
Homology between human and viral proteins is an established factor in viral-or vaccine-
induced autoimmunity. Failure of SARS and MERS vaccines in animal trials involved …

Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Z Noorimotlagh, C Karami, SA Mirzaee… - International …, 2020 - Elsevier
The beginning of 2020 was marked as the emergence of a COVID-19 outbreak caused by a
new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Immunoreactive peptide maps of SARS-CoV-2

N Mishra, X Huang, S Joshi, C Guo, J Ng… - Communications …, 2021 - nature.com
Serodiagnosis of SARS-CoV-2 infection is impeded by immunological cross-reactivity
among the human coronaviruses (HCoVs): SARS-CoV-2, SARS-CoV-1, MERS-CoV, OC43 …

Peptide microarray‐based analysis of antibody responses to SARS‐CoV‐2 identifies unique epitopes with potential for diagnostic test development

P Holenya, PJ Lange, U Reimer… - European Journal of …, 2021 - Wiley Online Library
Humoral immunity to the Severe Adult Respiratory Syndrome (SARS) Coronavirus (CoV)‐2
is not fully understood yet but is a crucial factor of immune protection. The possibility of …