Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

This review emphasizes how translation from bench research to clinical knowledge and vice
versa has resulted in considerable progress in understanding the immunopathogenesis of …

Psoriasis vulgaris is a chronic, debilitating skin disease that affects millions of people
worldwide. There is no mouse model that accurately reproduces all facets of the disease, but …

Psoriasis vulgaris is a multi-factorial heritable disease characterized by severe inflammation
resulting in poorly differentiated, hyperproliferative keratinocytes. Recent advances in …

Psoriasis is caused by a complex interplay between the immune system, psoriasis-
associated susceptibility loci, autoantigens, and multiple environmental factors. Over the last …

Psoriasis is a complex chronic inflammatory skin disease caused by the dynamic interplay
between multiple genetic risk foci, environmental risk factors, and excessive immunological …

Psoriasis is a multifactorial recalcitrant inflammatory skin disease characterized by
bothersome scaly reddish plaques especially on frequently chafed body parts, such as the …

Psoriasis is an inflammatory skin disease with complex pathogenesis and multiple
etiological factors. Besides the essential role of autoreactive T cells and constellation of …

Psoriasis is a complex chronic inflammatory cutaneous disorder. To date, robust molecular
mechanisms of psoriasis have been reported. Among diverse aberrant immunopathogenetic …

T helper (Th) cells producing interleukin (IL)-17, IL-22, and tumor necrosis factor (TNF) form
the key T cell population driving psoriasis pathogenesis. They orchestrate the inflammation …