Plasma growth differentiation factor 15 is associated with weight loss and mortality in cancer patients
L Lerner, TG Hayes, N Tao, B Krieger… - Journal of cachexia …, 2015 - Wiley Online Library
Background Cancer‐related weight loss is associated with increased inflammation and
decreased survival. The novel inflammatory mediator growth differentiation factor (GDF) 15 …
decreased survival. The novel inflammatory mediator growth differentiation factor (GDF) 15 …
Growth differentiating factor-15 (GDF-15): A potential biomarker and therapeutic target for cancer-associated weight loss
L Lerner, J Gyuris, R Nicoletti, J Gifford… - Oncology …, 2016 - spandidos-publications.com
Abstract Growth differentiating factor-15 (GDF-15), also known as macrophage inhibiting
factor‑1, is a member of the transforming growth factor‑β superfamily, which has been …
factor‑1, is a member of the transforming growth factor‑β superfamily, which has been …
Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia
Growth differentiation factor 15 or macrophage inhibitory cytokine-1 (GDF15/MIC-1) is a
divergent member of the transforming growth factor β superfamily and has a diverse …
divergent member of the transforming growth factor β superfamily and has a diverse …
[HTML][HTML] GDF15/GFRAL pathway as a metabolic signature for cachexia in patients with cancer
Cachexia is a metabolic mutiny that directly reduces life expectancy in chronic conditions
such as cancer. The underlying mechanisms associated with cachexia involve inflammation …
such as cancer. The underlying mechanisms associated with cachexia involve inflammation …
Growth differentiation factor 15 is a promising diagnostic and prognostic biomarker in colorectal cancer
Although various studies have demonstrated that growth differentiation factor 15 (GDF 15)
might be a potential diagnostic and prognostic marker in colorectal cancer (CRC) patients …
might be a potential diagnostic and prognostic marker in colorectal cancer (CRC) patients …
The relationship between insulin resistance and the cardiovascular biomarker growth differentiation factor-15 in obese patients
G Vila, M Riedl, C Anderwald, M Resl… - Clinical …, 2011 - academic.oup.com
BACKGROUND Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine
linked to obesity comorbidities such as cardiovascular disease, inflammation, and cancer …
linked to obesity comorbidities such as cardiovascular disease, inflammation, and cancer …
Clinical significance of growth differentiation factor 11 in colorectal cancer
T Yokoe, T Ohmachi, H Inoue… - International …, 2007 - spandidos-publications.com
Abstract Growth differentiation factor 11 (GDF11), a member of the transforming growth
factor-β superfamily and bone morphogenetic protein (BMP) subfamily, plays a role in …
factor-β superfamily and bone morphogenetic protein (BMP) subfamily, plays a role in …
Changes in systemic GDF15 across the adult lifespan and their impact on maximal muscle power: the Copenhagen Sarcopenia Study
J Alcazar, U Frandsen, T Prokhorova… - Journal of Cachexia …, 2021 - Wiley Online Library
Background Although growth differentiation factor 15 (GDF15) is known to increase with
disease and is associated with low physical performance, the role of GDF15 in normal …
disease and is associated with low physical performance, the role of GDF15 in normal …
Growth differentiation factor-15 as a biomarker for sarcopenia in aging humans and mice
Sarcopenia is a pathologic status characterized by impaired muscle strength or function
accompanying decreased muscle mass. It results in increased vulnerability to chronic …
accompanying decreased muscle mass. It results in increased vulnerability to chronic …
Bioactivity and prognostic significance of growth differentiation factor GDF15 secreted by bone marrow mesenchymal stem cells in multiple myeloma
J Corre, E Labat, N Espagnolle, B Hébraud… - Cancer research, 2012 - AACR
Overexpression of growth differentiation factor 15 (GDF15) by bone marrow mesenchymal
stem cells occurs widely in patients with multiple myeloma, but the pathophysiologic effects …
stem cells occurs widely in patients with multiple myeloma, but the pathophysiologic effects …