Rocket-miR, a translational launchpad for miRNA-based antimicrobial drug development
Developing software tools that leverage biological data sets to accelerate drug discovery is
an important aspect of bioinformatic research. Here, we present a novel example: a web …
an important aspect of bioinformatic research. Here, we present a novel example: a web …
The current landscape of microRNAs (miRNAs) in bacterial pneumonia: opportunities and challenges
F Zhang, Y Zhou, J Ding - Cellular & molecular biology letters, 2022 - Springer
MicroRNAs (miRNAs), which were initially discovered in Caenorhabditis elegans, can
regulate gene expression by recognizing cognate sequences and interfering with the …
regulate gene expression by recognizing cognate sequences and interfering with the …
A miRNA host response signature accurately discriminates acute respiratory infection etiologies
Background: Acute respiratory infections (ARIs) are the leading indication for antibacterial
prescriptions despite a viral etiology in the majority of cases. The lack of available …
prescriptions despite a viral etiology in the majority of cases. The lack of available …
miRandb: a resource of online services for miRNA research
SH Aghaee-Bakhtiari, E Arefian… - Briefings in bioinformatics, 2018 - academic.oup.com
Recent discovery of thousands of small and large noncoding RNAs, in parallel to technical
improvements enabling scientists to study the transcriptome in much higher depth, has …
improvements enabling scientists to study the transcriptome in much higher depth, has …
An in silico analysis of microRNAs: mining the miRNAome
Systematic analysis of literature-and experimentally-derived datasets using text mining with
ontological enrichment and network modeling revealed global trends in the microRNA …
ontological enrichment and network modeling revealed global trends in the microRNA …
Machine learning in the development of targeting microRNAs in human disease
A microRNA is a small, single-stranded, non-coding ribonucleic acid that plays a crucial role
in RNA silencing and can regulate gene expression. With the in-depth study of miRNA in …
in RNA silencing and can regulate gene expression. With the in-depth study of miRNA in …
Tools4miRs–one place to gather all the tools for miRNA analysis
A Lukasik, M Wójcikowski, P Zielenkiewicz - Bioinformatics, 2016 - academic.oup.com
MiRNAs are short, non-coding molecules that negatively regulate gene expression and
thereby play several important roles in living organisms. Dozens of computational methods …
thereby play several important roles in living organisms. Dozens of computational methods …
Pharmaco-miR: linking microRNAs and drug effects
JL Rukov, R Wilentzik, I Jaffe, J Vinther… - Briefings in …, 2014 - academic.oup.com
MicroRNAs (miRNAs) are short regulatory RNAs that down-regulate gene expression. They
are essential for cell homeostasis and active in many disease states. A major discovery is …
are essential for cell homeostasis and active in many disease states. A major discovery is …
MicroRNA biomarkers for infectious diseases: from basic research to biosensing
In the pursuit of improved diagnostic tests for infectious diseases, several classes of
molecules have been scrutinized as prospective biomarkers. Small (18–22 nucleotide), non …
molecules have been scrutinized as prospective biomarkers. Small (18–22 nucleotide), non …
Multifaceted roles of microRNAs in host-bacterial pathogen interaction
C Aguilar, M Mano, A Eulalio - Microbiology spectrum, 2019 - Am Soc Microbiol
MicroRNAs (miRNAs) are a well-characterized class of small noncoding RNAs that act as
major posttranscriptional regulators of gene expression. Accordingly, miRNAs have been …
major posttranscriptional regulators of gene expression. Accordingly, miRNAs have been …