Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group …
JH Krystal, W Abi-Saab, E Perry, DC D'Souza, N Liu… - …, 2005 - Springer
Rationale Some of the behavioral consequences of deficits in N-methyl-d-aspartate (NMDA)
glutamate receptor function are thought to arise from the disinhibition of cortical …
glutamate receptor function are thought to arise from the disinhibition of cortical …
A comparison of the effects of ketamine and phencyclidine with other antagonists of the NMDA receptor in rodent assays of attention and working memory
Rationale N-methyl-d-Aspartate receptor (NMDAR) antagonists such as ketamine induce
cognitive symptoms in man similar to those of schizophrenia and therefore might be useful …
cognitive symptoms in man similar to those of schizophrenia and therefore might be useful …
The effects of a subanesthetic dose of ketamine on verbal memory in normal volunteers
A Parwani, MA Weiler, TA Blaxton, D Warfel… - …, 2005 - Springer
Rationale N-methyl-d-aspartate (NMDA) glutamate receptor antagonists have been reported
to induce schizophrenia-like symptoms in humans, including memory impairments. Although …
to induce schizophrenia-like symptoms in humans, including memory impairments. Although …
NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers
AK Malhotra, DA Pinals, H Weingartner… - …, 1996 - Elsevier
A rapidly growing body of preclinical data has implicated the glutamatergic N-methyl-d-
aspartate (NMDA) receptor in memory and other cognitive processes. There is …
aspartate (NMDA) receptor in memory and other cognitive processes. There is …
Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis
JW Newcomer, NB Farber, V Jevtovic-Todorovic… - …, 1999 - Elsevier
N-methyl-D-aspartate (NMDA) glutamate receptor antagonists are reported to induce
schizophrenia-like symptoms in humans, including cognitive impairments. Shortcomings of …
schizophrenia-like symptoms in humans, including cognitive impairments. Shortcomings of …
Acute effects of ketamine on memory systems and psychotic symptoms in healthy volunteers
CJA Morgan, A Mofeez, B Brandner… - …, 2004 - nature.com
Abstract N-methyl-D-aspartate (NMDA) receptor antagonists have been demonstrated to
induce schizophrenia-like symptoms and cognitive impairment in humans. The NMDA …
induce schizophrenia-like symptoms and cognitive impairment in humans. The NMDA …
Selective cognitive impairments associated with NMDA receptor blockade in humans
Hypofunction of the N-methyl-D-aspartate receptor (NMDAR) may be involved in the
pathophysiology of schizophrenia. NMDAR antagonists like ketamine induce schizophrenia …
pathophysiology of schizophrenia. NMDAR antagonists like ketamine induce schizophrenia …
Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists
A Anand, DS Charney, DA Oren… - Archives of general …, 2000 - jamanetwork.com
Background The cognitive, behavioral, and mood effects ofN-methyl-D-aspartate (NMDA)
receptor antagonists, such as phencyclidine and ketamine, have been used to study the …
receptor antagonists, such as phencyclidine and ketamine, have been used to study the …
Functional interaction between NMDA and mGlu5 receptors: effects on working memory, instrumental learning, motor behaviors, and dopamine release
H Homayoun, MR Stefani, BW Adams… - …, 2004 - nature.com
Pharmacological manipulation of N-methyl-D-aspartate (NMDA) receptors may be critical for
the treatment of many neurological and psychiatric disorders. Metabotropic glutamate …
the treatment of many neurological and psychiatric disorders. Metabotropic glutamate …
Repeated injection of MK801: an animal model of schizophrenia?
EM Eyjolfsson, E Brenner, D Kondziella… - Neurochemistry …, 2006 - Elsevier
Glutamate-induced neurotoxicity plays an important role in neurological and psychiatric
diseases. Thus, much attention has been given to the potential neuroprotective role of …
diseases. Thus, much attention has been given to the potential neuroprotective role of …
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