Bone turnover markers (BTMs) are used widely, in both research and clinical practice. In the
last 20 years, much experience has been gained in measurement and interpretation of these …

Bone turnover includes two processes: resorption (removal of old bone) and formation
(laying down of new bone). N-terminal propeptide of type I procollagen (PINP) and C …

BACKGROUND Disorders of bone metabolism, most notably osteoporosis, are highly
prevalent and predispose to fractures, causing high patient morbidity and mortality …

Bone turnover markers (BTMs) are released during the bone remodelling cycle and are
measurable in blood or urine, reflecting bone remodelling rate. They have been useful in …

INTRODUCTION: Biochemical markers of bone turnover (BTMs) are important in
determining fracture risk in postmenopausal women; high levels being associated with …

Background: Biochemical markers of bone turnover (BTMs) provide useful information in the
diagnosis and management of metabolic bone diseases. Currently, there exist few …

Bone is a dynamic tissue which undergoes constant remodeling throughout the life span.
Bone turnover is balanced with coupling of bone formation and resorption at various rates …

The adult bone is continuously being remodelled to repair microdamage, preserve bone
strength and mechanical competence as well as maintain calcium homeostasis. Bone …

Bone turnover markers have clinical utility in the comprehensive evaluation of osteoporosis.
When interpreted with caution and with a good understanding of their natural variability …

Osteoporosis is the most common cause of fragility fractures. Bone remodelling is essential
for repairing damaged areas within bone to preserve bone strength and for assisting in …