[HTML][HTML] Tobacco-specific N-nitrosamines NNN and NNK levels in cigarette brands between 2000 and 2014

I Gunduz, A Kondylis, G Jaccard, JM Renaud… - Regulatory Toxicology …, 2016 - Elsevier
The evolution of the levels of tobacco-specific N-nitrosamines (TSNA), N-nitrosonornicotine
(NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mainstream (MS) …

Carcinogenic tobacco-specific N-nitrosamines in US cigarettes: three decades of remarkable neglect by the tobacco industry

I Stepanov, A Knezevich, L Zhang… - Tobacco …, 2012 - tobaccocontrol.bmj.com
Background Modification of tobacco curing methods and other changes in cigarette
manufacturing techniques could substantially reduce the levels of tobacco-specific …

Tobacco-specific nitrosamines in the tobacco and mainstream smoke of US commercial cigarettes

SH Edwards, LM Rossiter, KM Taylor… - Chemical research in …, 2017 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) are N-nitroso-derivatives of pyridine-alkaloids (eg,
nicotine) present in tobacco and cigarette smoke. Two TSNAs, N′-nitrosonornicotine (NNN) …

[HTML][HTML] TSNA levels in machine-generated mainstream cigarette smoke: 35 years of data

S Appleton, RM Olegario, PJ Lipowicz - Regulatory Toxicology and …, 2013 - Elsevier
This paper characterizes historical and current tobacco specific nitrosamine (TSNA) levels in
mainstream (MS) cigarette smoke of US commercial cigarettes. To conduct this analysis, we …

It is time to regulate carcinogenic tobacco-specific nitrosamines in cigarette tobacco

SS Hecht - Cancer Prevention Research, 2014 - AACR
Abstract The Family Smoking Prevention and Tobacco Control Act gives the US Food and
Drug Administration power to regulate tobacco products. This commentary calls for …

[PDF][PDF] Determination of tobacco specific nitrosamines in cigarette mainstream smoke: The CORESTA 2011 collaborative study

M Intorp, S Purkis, W Wagstaff - Contributions to Tobacco & Nicotine …, 2012 - sciendo.com
SUMMARY A CORESTA Recommended Method (CRM 75) has been developed and
published, applicable to the quantification of tobacco-specific nitrosamines (TSNAs) …

Tobacco-specific nitrosamines in tobacco from US brand and non-US brand cigarettes

DL Ashley, MD Beeson, DR Johnson… - Nicotine & tobacco …, 2003 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) are one of the major classes of carcinogens found in
tobacco products. As part of collaborative efforts to reduce tobacco use and resulting …

Reductions in the tobacco specific nitrosamine (TSNA) content of tobaccos taken from commercial Canadian cigarettes and corresponding reductions in TSNA …

WS Rickert, PJ Joza, M Sharifi, J Wu… - Regulatory Toxicology …, 2008 - Elsevier
Tobacco specific nitrosamines (TSNAs) are suspected to cause smoking-related neoplastic
diseases. The change from direct-fired to indirect-fired barns (aka kilns) for curing bright (aka …

Simultaneous determination of four tobacco-specific N-nitrosamines in mainstream smoke for Chinese Virginia cigarettes by liquid chromatography–tandem mass …

W Xiong, H Hou, X Jiang, G Tang, Q Hu - Analytica chimica acta, 2010 - Elsevier
A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for determining
four tobacco-specific N-nitrosamines (TSNAs) in mainstream smoke from Chinese Virginia …

Five-year yield variation in N-nitrosonornicotine and (4-methylnitrosoamino)-1-(3-pyridyl)-1-butanone from the smoke of commercial cigarette brands on the Japanese …

T Hyodo, K Minagawa, A Mikita - Regulatory Toxicology and Pharmacology, 2015 - Elsevier
This study reports on variation in the yields of N-nitrosonornicotine (NNN) and (4-
methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK) from the mainstream smoke of …