FIAMol-AB: A feature fusion and attention-based deep learning method for enhanced antibiotic discovery

S He, X Ye, L Dou, T Sakurai - Computers in Biology and Medicine, 2024 - Elsevier
Antibiotic resistance continues to be a growing concern for global health, accentuating the
need for novel antibiotic discoveries. Traditional methodologies in this field have relied …

Deep learning tools to accelerate antibiotic discovery

A Cesaro, M Bagheri, M Torres, F Wan… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction As machine learning (ML) and artificial intelligence (AI) expand to many
segments of our society, they are increasingly being used for drug discovery. Recent deep …

HMD-ARG: hierarchical multi-task deep learning for annotating antibiotic resistance genes

Y Li, Z Xu, W Han, H Cao, R Umarov, A Yan, M Fan… - Microbiome, 2021 - Springer
Background The spread of antibiotic resistance has become one of the most urgent threats
to global health, which is estimated to cause 700,000 deaths each year globally. Its …

Deep learning and antibiotic resistance

SL Popa, C Pop, MO Dita, VD Brata, R Bolchis… - Antibiotics, 2022 - mdpi.com
Antibiotic resistance (AR) is a naturally occurring phenomenon with the capacity to render
useless all known antibiotics in the fight against bacterial infections. Although bacterial …

[PDF][PDF] Deep Learning and Antibiotic Resistance. Antibiotics 2022, 11, 1674

SL Popa, C Pop, MO Dita, VD Brata, R Bolchis… - 2022 - academia.edu
Antibiotic resistance (AR) is a naturally occurring phenomenon with the capacity to render
useless all known antibiotics in the fight against bacterial infections. Although bacterial …

AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens

C Li, D Sutherland, SA Hammond, C Yang, F Taho… - BMC genomics, 2022 - Springer
Background Antibiotic resistance is a growing global health concern prompting researchers
to seek alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) are attracting …

A brief guide to machine learning for antibiotic discovery

G Liu, JM Stokes - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Rising antibiotic resistance requires novel approaches to antibiotic
discovery.•Machine learning methods can accelerate the antibiotic discovery …

[HTML][HTML] A deep learning approach to antibiotic discovery

JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz… - Cell, 2020 - cell.com
Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to
discover new antibiotics. To address this challenge, we trained a deep neural network …

Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii

G Liu, DB Catacutan, K Rathod, K Swanson… - Nature Chemical …, 2023 - nature.com
Acinetobacter baumannii is a nosocomial Gram-negative pathogen that often displays
multidrug resistance. Discovering new antibiotics against A. baumannii has proven …

Multi-scale temporal convolutional networks and continual learning based in silico discovery of alternative antibiotics to combat multi-drug resistance

V Singh, S Shrivastava, SK Singh, A Kumar… - Expert Systems with …, 2023 - Elsevier
The high incidence of diseases caused by multi-drug resistant (MDR) pathogens combined
with the shortage of effective antibiotics has necessitated the development of in-silico …