Particulate hexavalent chromium alters microRNAs in human lung cells that target key carcinogenic pathways
Abstract Hexavalent chromium [Cr (VI)] is a global environmental pollutant and human lung
carcinogen. However, the mechanisms of Cr (VI) carcinogenesis are not well defined. Cr (VI) …
carcinogen. However, the mechanisms of Cr (VI) carcinogenesis are not well defined. Cr (VI) …
Transcriptomic analysis reveals particulate hexavalent chromium regulates key inflammatory pathways in human lung fibroblasts as a possible mechanism of …
Abstract Hexavalent chromium [Cr (VI)] is considered a major environmental health concern
and lung carcinogen. However, the exact mechanism by which Cr (VI) causes lung cancer in …
and lung carcinogen. However, the exact mechanism by which Cr (VI) causes lung cancer in …
Epigenetic and epitranscriptomic mechanisms of chromium carcinogenesis
Abstract Hexavalent chromium [Cr (VI)], a Group I carcinogen classified by the International
Agency for Research on Cancer (IARC), represents one of the most common occupational …
Agency for Research on Cancer (IARC), represents one of the most common occupational …
[HTML][HTML] Circulating lung-cancer-related non-coding RNAs are associated with occupational exposure to hexavalent chromium–A cross-sectional study within the …
Z Jiang, R Person, T Lundh, D Pineda, M Engfeldt… - Environment …, 2024 - Elsevier
Abstract Background Hexavalent chromium (Cr (Ⅵ)) is classified as a group 1 human
carcinogen and increases the risk of lung cancer. Non-coding RNAs (ncRNAs) have key …
carcinogen and increases the risk of lung cancer. Non-coding RNAs (ncRNAs) have key …
Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis
JE Rager, M Suh, GA Chappell, CM Thompson… - Toxicology letters, 2019 - Elsevier
Inhalation exposure to hexavalent chromium [Cr (VI)] is associated with increased risk of
lung cancer with a mode of action (MOA) postulated to involve non-mutagenic key events …
lung cancer with a mode of action (MOA) postulated to involve non-mutagenic key events …
[HTML][HTML] Comparison of gene expression profiles in chromate transformed BEAS-2B cells
Background Hexavalent chromium [Cr (VI)] is a potent human carcinogen. Occupational
exposure has been associated with increased risk of respiratory cancer. Multiple …
exposure has been associated with increased risk of respiratory cancer. Multiple …
Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial …
Abstract Hexavalent chromium [Cr (VI)] is a human lung carcinogen with widespread
exposure risks. Cr (VI) causes DNA double strand breaks that if unrepaired, progress into …
exposure risks. Cr (VI) causes DNA double strand breaks that if unrepaired, progress into …
Molecular and epigenetic mechanisms of Cr (VI)-induced carcinogenesis
Chromium (Cr) is a naturally occurring metallic element found in the Earth's crust. While
trivalent chromium ([Cr (III)] is considered non-carcinogenic, hexavalent chromium [Cr (VI)] …
trivalent chromium ([Cr (III)] is considered non-carcinogenic, hexavalent chromium [Cr (VI)] …
[HTML][HTML] The Oncogenic and Tumor Suppressive Long Non-Coding RNA–microRNA–Messenger RNA Regulatory Axes Identified by Analyzing Multiple Platform …
Chronic exposure to hexavalent chromium (Cr (VI)) causes lung cancer in humans,
however, the underlying mechanism has not been well understood. Long non-coding RNAs …
however, the underlying mechanism has not been well understood. Long non-coding RNAs …
[PDF][PDF] Hexavalent chromium exposure, genomic instability and lung cancer
AM Urbano, CFD Rodrigues, MC Alpoim - Gene Ther. Mol. Biol, 2008 - Citeseer
Worldwide, several million workers experience occupational exposure to different
hexavalent chromium [Cr (VI)] compounds (chromates) which have long been recognized as …
hexavalent chromium [Cr (VI)] compounds (chromates) which have long been recognized as …