International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis

X Chen, AS Tsvetkov, HM Shen, C Isidoro… - Autophagy, 2024 - Taylor & Francis
Macroautophagy/autophagy is a complex degradation process with a dual role in cell death
that is influenced by the cell types that are involved and the stressors they are exposed to …

[PDF][PDF] Autophagy-dependent ferroptosis: machinery and regulation

J Liu, F Kuang, G Kroemer, DJ Klionsky, R Kang… - Cell chemical …, 2020 - cell.com
Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved cellular
process capable of degrading various biological molecules (eg, protein, glycogen, lipids …

Autophagy-dependent ferroptosis in cancer

F Chen, X Cai, R Kang, J Liu, D Tang - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Autophagy is a self-degrading process that determines cell fate in response to
various environmental stresses. In contrast to autophagy-mediated cell survival, the signals …

[HTML][HTML] Autophagy mediates an amplification loop during ferroptosis

S Lee, N Hwang, BG Seok, S Lee, SJ Lee… - Cell Death & …, 2023 - nature.com
Ferroptosis, a programmed cell death, has been identified and associated with cancer and
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …

Autophagy and ferroptosis—what is the connection?

R Kang, D Tang - Current pathobiology reports, 2017 - Springer
Abstract Purpose of Review Autophagy is a conserved intracellular degradation system and
plays a dual role in cell death, depending on context and phase. Ferroptosis is a new form of …

[HTML][HTML] Ferroptosis and its modulation by autophagy in light of the pathogenesis of lysosomal storage diseases

K Pierzynowska, E Rintz, L Gaffke, G Węgrzyn - Cells, 2021 - mdpi.com
Ferroptosis is one of the recently described types of cell death which is dependent on many
factors, including the accumulation of iron and lipid peroxidation. Its induction requires …

Autophagy promotes ferroptosis by degradation of ferritin

W Hou, Y Xie, X Song, X Sun, MT Lotze, HJ Zeh III… - Autophagy, 2016 - Taylor & Francis
Macroautophagy/autophagy is an evolutionarily conserved degradation pathway that
maintains homeostasis. Ferroptosis, a novel form of regulated cell death, is characterized by …

Correlation of ferroptosis and other types of cell death in neurodegenerative diseases

X Dang, X Huan, X Du, X Chen, M Bi, C Yan, Q Jiao… - Neuroscience …, 2022 - Springer
Ferroptosis is defined as an iron-dependent, non-apoptotic cell death pathway, with specific
morphological phenotypes and biochemical changes. There is a growing realization that …

Organelle-specific regulation of ferroptosis

X Chen, R Kang, G Kroemer, D Tang - Cell Death & Differentiation, 2021 - nature.com
Ferroptosis, a cell death modality characterized by iron-dependent lipid peroxidation, is
involved in the development of multiple pathological conditions, including ischemic tissue …

Ferroptosis is a type of autophagy-dependent cell death

B Zhou, J Liu, R Kang, DJ Klionsky, G Kroemer… - Seminars in cancer …, 2020 - Elsevier
Macroautophagy (hereafter referred to as autophagy) involves an intracellular degradation
and recycling system that, in a context-dependent manner, can either promote cell survival …