Obesity alters adipose tissue metabolic and endocrine function and leads to an increased
release of fatty acids, hormones, and proinflammatory molecules that contribute to obesity …

Obesity is associated with infiltration of macrophages into adipose tissue (AT), contributing
to insulin resistance and diabetes. However, relatively little is known regarding the origin of …

Background. Obesity is a global health problem of epidemic proportions, which is
characterized by increased adipose tissue (AT) mass and significant repercussions in …

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Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …

The roles of adipokines, proinflammatory cytokines, and adipose tissue macrophages in
obesity-associated insulin resistance have been explored in both animal and human …

Obesity is associated with a proinflammatory state, with macrophage infiltration into adipose
tissue. We tested the hypothesis that communication between macrophages and adipocytes …

Severe obesity represents a major risk factor for the development of type 2 diabetes mellitus
(T2DM). Due to the strong association of obesity and diabetes, the term “diabesity” was …

Obesity is associated with adverse alterations in adipose tissue that predispose to metabolic
dysregulation. These adverse alterations include accumulation of inflammatory …

Context Adipose tissue is increasingly recognized as an active endocrine organ with many
secretory products and part of the innate immune system. With obesity, macrophages …