Role of the blood–brain barrier in the nutrition of the central nervous system
P Campos-Bedolla, FR Walter, S Veszelka… - Archives of medical …, 2014 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex interface between the blood and
the central nervous system regulating brain homeostasis. Major functions of the BBB include …
the central nervous system regulating brain homeostasis. Major functions of the BBB include …
A review of blood-brain barrier transport techniques
QR Smith - The Blood-Brain Barrier: Biology and Research …, 2003 - Springer
The blood-brain barrier (BBB) is a unique dynamic regulatory interface situated at the border
between the blood stream and the brain extracellular (or interstitial) fluid. As the …
between the blood stream and the brain extracellular (or interstitial) fluid. As the …
Transporter-mediated permeation of drugs across the blood–brain barrier
I Tamai, A Tsuji - Journal of pharmaceutical sciences, 2000 - Elsevier
Drug distribution into the brain is strictly regulated by the presence of the blood–brain barrier
(BBB) that is formed by brain capillary endothelial cells. Since the endothelial cells are …
(BBB) that is formed by brain capillary endothelial cells. Since the endothelial cells are …
Transendothelial transport and its role in therapeutics
RK Upadhyay - International scholarly research notices, 2014 - Wiley Online Library
Present review paper highlights role of BBB in endothelial transport of various substances
into the brain. More specifically, permeability functions of BBB in transendothelial transport …
into the brain. More specifically, permeability functions of BBB in transendothelial transport …
Contribution of carrier-mediated transport systems to the blood–brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery …
S Ohtsuki, T Terasaki - Pharmaceutical research, 2007 - Springer
The blood–brain barrier (BBB) forms an interface between the circulating blood and the
brain and possesses various carrier-mediated transport systems for small molecules to …
brain and possesses various carrier-mediated transport systems for small molecules to …
Blood-brain barrier transport of nutrients.
WM Pardridge - 1986 - cabidigitallibrary.org
Brain metabolism and function are acutely regulated by nutrient availability in the diet,
because many pathways of brain nutrient metabolism are controlled by precursor availability …
because many pathways of brain nutrient metabolism are controlled by precursor availability …
Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases
R Gabathuler - Neurobiology of disease, 2010 - Elsevier
The central nervous system is protected by barriers which control the entry of compounds
into the brain, thereby regulating brain homeostasis. The blood–brain barrier, formed by the …
into the brain, thereby regulating brain homeostasis. The blood–brain barrier, formed by the …
Brain-to-blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier: an overview of biology and methodology
T Terasaki, S Ohtsuki - NeuroRx, 2005 - Springer
In the past decade, research into P-glycoprotein involving the blood-brain barrier (BBB) has
seen a shift in the concept of the BBB as a structural barrier to that of a functional barrier for …
seen a shift in the concept of the BBB as a structural barrier to that of a functional barrier for …
[HTML][HTML] An overview of the multiple functions of the blood-brain barrier
AL Betz - NIDA Res Monogr, 1992 - books.google.com
The existence of a permeability barrier between the blood and the brain has been known for
more than a century; however, during the past two decades there has been a tremendous …
more than a century; however, during the past two decades there has been a tremendous …
Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules
Barriers are the hallmark of a healthy physiology, blood-brain barrier (BBB) being a tough
nut to crack for most of the antigens and chemical substances. The presence of tight …
nut to crack for most of the antigens and chemical substances. The presence of tight …