Alendronate (ALN) is a second-generation bisphosphonate widely used for osteoporosis
and cancer-induced bone lesions. Many studies have confirmed a strong relationship …

Bisphosphonates (BPs) are widely used to treat several metabolic and oncological diseases
affecting the skeletal system. Despite BPs' well-known therapeutic potential, they also …

Bisphosphonate-induced osteonecrosis of the jaw (BIONJ) is a commonly encountered side
effect of Bisphosphonates (BPs). Although certain aspects of BIONJ have been studied, the …

Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a severe adverse reaction,
which results in progressive bone destruction in the maxillofacial region of patients. To date …

Background The onset mechanism for bisphosphonate‐related osteonecrosis of the jaw
(BRONJ) has been reported, with a focus on bone remodeling, biofilm formation, and …

Abstract Objectives Although bisphosphonates (BPs) are known to be associated with
osteonecrosis of the maxilla, the precise effects of BPs on bone metabolism in human …

Periodontitis is a common chronic inflammatory oral disease. The objective of periodontal
treatment is to control infection whilst regenerating damaged periodontal tissue. The present …

Polydopamine‐templated hydroxyapatite (tHA) is a type of nano‐biomaterial that can
promote osteogenesis in bone tissue engineering. However, high concentrations of tHA …

Periodontitis is one of the main causes of tooth loss and has been confirmed as the sixth
complication of diabetes. Metformin promotes the osteogenic differentiation of stem cells …

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a clinical condition that
specifically occurs in the oral cavity, characterized by retarded wound healing in oral …