Glucocorticoids
The most effective anti-inflammatory drugs used to treat patients with airways disease are
topical glucocorticosteroids (GCs). These act on virtually all cells within the airway to …
topical glucocorticosteroids (GCs). These act on virtually all cells within the airway to …
Glucocorticoids: mechanisms of action and anti‐inflammatory potential in asthma
VHJ Van Der Velden - Mediators of inflammation, 1998 - Wiley Online Library
Glucocorticoids are potent inhibitors of inflammatory processes and are widely used in the
treatment of asthma. The anti‐inflammatory effects are mediated either by direct binding of …
treatment of asthma. The anti‐inflammatory effects are mediated either by direct binding of …
Efficacy and safety of inhaled corticosteroids in asthma
PJ Barnes, S Pedersen - American Review of Respiratory Disease, 1993 - atsjournals.org
Inhaled glucocorticosteroids have now become first-line therapy for the treatment of chronic
asthma in many countries. They are the most effective asthma therapy currently available …
asthma in many countries. They are the most effective asthma therapy currently available …
Issues in the use of inhaled glucocorticoids. The Asthma Clinical Research Network.
AK Kamada, SJ Szefler, RJ Martin… - American journal of …, 1996 - atsjournals.org
Asthma is now regarded as an inflammatory disease, and inhaled glucocorticoids (iGCs) are
recommended earlier in the course of treatment of patients with this disorder. Although iGCs …
recommended earlier in the course of treatment of patients with this disorder. Although iGCs …
Mechanisms of glucocorticoid action and insensitivity in airways disease
C Boardman, L Chachi, A Gavrila, CR Keenan… - Pulmonary …, 2014 - Elsevier
Glucocorticoids are the mainstay for the treatment of chronic inflammatory diseases
including asthma and chronic obstructive pulmonary disease (COPD). However, it has been …
including asthma and chronic obstructive pulmonary disease (COPD). However, it has been …
Glucocorticoid therapy for asthma: clinical pharmacology
SJ Szefler - Journal of allergy and clinical immunology, 1991 - Elsevier
We are now well aware that inflammation plays an important role in the pathogenesis of
asthma. This awareness comes at a time when we question the etiology of increased …
asthma. This awareness comes at a time when we question the etiology of increased …
Clinical pharmacology of corticosteroids
DM Williams - Respiratory care, 2018 - rc.rcjournal.com
Corticosteroids have numerous applications in treating inflammation and diseases of
immune function based on their significant anti-inflammatory and immunosuppressive …
immune function based on their significant anti-inflammatory and immunosuppressive …
Update on glucocorticoid action and resistance
Extensive development of inhaled and oral glucocorticoids has resulted in highly potent
molecules that have been optimized to target activity to the lung and minimize systemic …
molecules that have been optimized to target activity to the lung and minimize systemic …
Inhaled glucocorticoids for asthma
PJ Barnes - New England Journal of Medicine, 1995 - Mass Medical Soc
Glucocorticoids are the most effective therapy available for patients with asthma. They may
be administered either orally or, much more safely, by inhalation. With the recognition that …
be administered either orally or, much more safely, by inhalation. With the recognition that …
[引用][C] Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids
M Johnson - Journal of Allergy and Clinical Immunology, 1996 - Elsevier
Research during the past two decades has shown that the inflammatory component of
bronchial asthma has a highly complex and multifactorial pathophysiology. Inhaled …
bronchial asthma has a highly complex and multifactorial pathophysiology. Inhaled …