Background Environmental exposures play a critical role in the genesis of some child mental
health problems. Methods We open with a discussion of children's vulnerability to neurotoxic …

This paper summarizes the deliberations of a work group charged with addressing specific
questions relevant to risk estimation in developmental neurotoxicology. We focused on eight …

Principles and practices of pediatric neurotoxicology are reviewed here with the purpose of
guiding the design and execution of the planned National Children's Study. The developing …

The brain of infants and children is uniquely sensitive to environmental neurotoxicants at
levels far below those that are known to harm adults. There are multiple windows of …

Background Studies of early-life neurotoxicant exposure have not been designed, analyzed,
or interpreted in the context of a fully developmental perspective. Objectives The goal of this …

Learning disabilities, attention deficit hyperactivity disorder, developmental delays, and
emotional and behavioral problems are among childhood disabilities of increasing concern …

Background The outcomes of exposure to neurotoxic chemicals early in life depend on the
properties of both the chemical and the host's environment. When our questions focus on the …

Alterations in nervous system function after exposure to a developmental neurotoxicant may
be identified and characterized using neurobehavioral methods. A number of methods can …

Abstract Purpose of Review With the incidence of neurodevelopmental disorders on the rise,
it is imperative to identify and understand the mechanisms by which environmental …

Little attention has been invested in exploring the possibility that the nature or magnitude of
a neurotoxicant's health impact on children depends on host characteristics (eg, sex, age) or …