Chlamydia trachomatis type III secretion: evidence for a functional apparatus during early‐cycle development

KA Fields, DJ Mead, CA Dooley… - Molecular …, 2003 - Wiley Online Library
The obligate intracellular bacterium Chlamydia trachomatis occupies a parasitophorous
vacuole termed an inclusion. During its intracellular developmental cycle, C. trachomatis …

Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism

KA Fields, T Hackstadt - Molecular microbiology, 2000 - Wiley Online Library
The medically significant, obligate intracellular pathogen Chlamydia trachomatis replicates
within vacuoles termed inclusions. A developmental cycle is initiated after entry into a host …

A directed screen for chlamydial proteins secreted by a type III mechanism identifies a translocated protein and numerous other new candidates

A Subtil, C Delevoye, ME Balañá… - Molecular …, 2005 - Wiley Online Library
Chlamydiae are strict intracellular parasites that induce their internalization upon contact
with the host cell and grow inside an intracellular compartment called an inclusion. They …

Identification of a family of effectors secreted by the type III secretion system that are conserved in pathogenic Chlamydiae

S Muschiol, G Boncompain, F Vromman… - Infection and …, 2011 - Am Soc Microbiol
Chlamydiae are Gram-negative, obligate intracellular pathogens that replicate within a
membrane-bounded compartment termed an inclusion. Throughout their development, they …

Evidence that CT694 is a novel Chlamydia trachomatis T3S substrate capable of functioning during invasion or early cycle development

S Hower, K Wolf, KA Fields - Molecular microbiology, 2009 - Wiley Online Library
Chlamydia trachomatis is an obligate intracellular parasite, occupies a membrane‐bound
vacuole throughout development and is capable of manipulating the eukaryotic host by …

Expression and localization of predicted inclusion membrane proteins in Chlamydia trachomatis

MM Weber, LD Bauler, J Lam… - Infection and immunity, 2015 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular pathogen that replicates in a membrane-
bound vacuole termed the inclusion. Early in the infection cycle, the pathogen extensively …

Identification of Chlamydia trachomatis CT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus

AS Hobolt-Pedersen, G Christiansen… - FEMS Immunology & …, 2009 - academic.oup.com
Chlamydiae are obligate intracellular bacteria, developing inside host cells within
chlamydial inclusions. From these inclusions, the chlamydiae secrete proteins into the host …

Treatment of Chlamydia trachomatis with a small molecule inhibitor of the Yersinia type III secretion system disrupts progression of the chlamydial developmental …

K Wolf, HJ Betts, B Chellas‐Géry, S Hower… - Molecular …, 2006 - Wiley Online Library
The obligate intracellular bacterium Chlamydia trachomatis possesses a biphasic
developmental cycle that is manifested by differentiation of infectious, metabolically inert …

Identification and characterization of a Chlamydia trachomatis early operon encoding four novel inclusion membrane proteins

MA Scidmore‐Carlson, EI Shaw… - Molecular …, 1999 - Wiley Online Library
Chlamydia trachomatis is a bacterial obligate intracellular parasite that replicates within a
vacuole, termed an inclusion, that does not fuse with lysosomes. Within 2 h after …

Type III secretion in Chlamydia

EA Rucks - Microbiology and Molecular Biology Reviews, 2023 - Am Soc Microbiol
Type III secretion systems (T3SSs) are utilized by Gram-negative pathogens to enhance
their pathogenesis. This secretion system is associated with the delivery of effectors through …