[HTML][HTML] Molecular targeting for treatment of human T-lymphotropic virus type 1 infection

A Soltani, SI Hashemy, FZ Avval, A Soleimani… - Biomedicine & …, 2019 - Elsevier
Human T-cell lymphotropic virus type 1 (HTLV-1) infection is linked to adult T-cell leukemia-
lymphoma (ATLL) and HTLV-I-associated myelopathy/tropical spastic paraparesis …

Drug targets in human T-lymphotropic virus type 1 (HTLV-1) infection

P Boross, P Bagossi, IT Weber… - Infectious Disorders-Drug …, 2009 - ingentaconnect.com
Human T-lymphotropic virus type 1 (HTLV-1), the first known human retrovirus, induces
various human diseases with a long latency period. The mechanism by which the virus …

HTLV-1 HBZ viral protein: a key player in HTLV-1 mediated diseases

M Baratella, G Forlani, RS Accolla - Frontiers in microbiology, 2017 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus that has
infected 10–15 million people worldwide. After a long latency, 3–5% of infected individuals …

Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL

M Kannagi, A Hasegawa, Y Nagano, S Kimpara… - Retrovirology, 2019 - Springer
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL),
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other …

How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy

A Pasquier, S Alais, L Roux, MI Thoulouze… - Frontiers in …, 2018 - frontiersin.org
Five to ten million individuals are infected by Human T-cell Leukemia Virus type 1 (HTLV-1).
HTLV-1 is transmitted through prolonged breast-feeding, by sexual contacts and by …

Future perspectives on drug targeting in adult T cell leukemia-lymphoma

F Marino-Merlo, A Mastino, S Grelli… - Frontiers in …, 2018 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T cell
leukemia/lymphoma (ATL), HTLV-1 associated myelopathy (HAM/TSP), and of a number of …

The protease of human T-cell leukemia virus type-1 is a potential therapeutic target

J Tozser, IT Weber - Current pharmaceutical design, 2007 - ingentaconnect.com
Human T-cell leukemia virus type-1 (HTLV-1) is associated with a number of human
diseases. Although the mechanism by which the virus causes diseases is still not known …

Role of the HTLV-1 viral factors in the induction of apoptosis

M Karimi, H Mohammadi, M Hemmatzadeh… - Biomedicine & …, 2017 - Elsevier
Adult T-cell leukemia (ATL) and HTLV-1-associated Myelopathy/Tropical Spastic
Paraparesis (HAM/TSP) are the two main diseases that are caused by the HTLV-1 virus …

Locking the two ends of tetrapeptidic HTLV-I protease inhibitors inside the enzyme

M Zhang, JT Nguyen, HO Kumada, T Kimura… - Bioorganic & medicinal …, 2008 - Elsevier
Adult T-cell leukemia and tropical spastic paraparesis/HTLV-I-associated myelopathy are
only some of the more common end results of an infection with a human T-cell leukemia …

Role of HTLV-1 Tax and HBZ in the pathogenesis of HAM/TSP

Y Enose-Akahata, A Vellucci, S Jacobson - Frontiers in microbiology, 2017 - frontiersin.org
Human T cell lymphotropic virus type 1 (HTLV-1) infection can lead to development of adult
T cell leukemia/lymphoma (ATL) or HTLV-1-associated myelopathy/tropical spastic …