Stable isotope labeling by amino acids in cell culture (SILAC) is a simple, robust, yet
powerful approach in mass spectrometry (MS)-based quantitative proteomics. SILAC labels …

Mass spectrometry (MS)-based proteomics is increasingly applied in a quantitative format,
often based on labeling of samples with stable isotopes that are introduced chemically or …

Stable isotope labeling with amino acids in cell culture (SILAC) is a simple in vivo labeling
strategy for mass spectrometry-based quantitative proteomics. It relies on the metabolic …

Stable isotope labeling by amino acids in cell culture (SILAC) has become a popular
labeling strategy for peptide quantitation in proteomics experiments. If the SILAC technology …

Publisher Summary Analysis by combined liquid chromatographic separation and mass
spectrometry (LC-MS) is rapidly becoming the most popular and effective approach for large …

Stable isotope labeling by amino acids (SILAC) metabolically encodes cell populations for
protein quantification by mass spectrometry. SILAC was introduced in 2002 and the field of …

Quantitative proteomics has traditionally been performed by two-dimensional gel
electrophoresis, but recently, mass spectrometric methods based on stable isotope …

Researchers in many biological areas now routinely characterize proteins by mass
spectrometry. Among the many formats for quantitative proteomics, stable-isotope labelling …

We have recently described a method, stable isotope labeling by amino acids in cell culture
(SILAC) for the accurate quantitation of relative protein abundances. Cells were …

Stable isotope labeling with amino acids in cell culture (SILAC) is a simple and
straightforward approach for in vivo incorporation of a tag into proteins for relative …