Expression of protein-coding genes in eukaryotes relies on the coordinated action of many
sophisticated molecular machineries. Transcription produces precursor mRNAs (pre …

Fully processed mRNAs are exported to the cytoplasm where they direct protein synthesis.
Export of mRNAs is mediated by a conserved heterodimeric transport receptor (known as …

Release of properly processed and assembled mRNPs from the actively transcribing genes,
movement of the mRNPs through the interchromatin and interaction with the Nuclear Pore …

Transcription is a central function occurring in the nucleus of eukaryotic cells in coordination
with other nuclear processes. During transcription, the nascent pre-mRNA associates with …

Cellular mRNAs are produced in the nucleus and must be exported to the cytoplasm to allow
for their translation into proteins. Recruitment of export factors to nascent mRNA starts …

The cell nucleus is an intricate organelle that coordinates multiple activities that are
associated with DNA replication and gene expression. In all eukaryotes, it stores the genetic …

Export of mRNA from the nucleus to the cytoplasm is a critical process for all eukaryotic gene
expression. As mRNA is synthesized, it is packaged with a myriad of RNA‐binding proteins …

mRNAs are transported from the nucleus to the cytoplasm by a machinery conserved from
yeast to humans. Previous studies showed that mRNA export factors are loaded on nascent …

Nuclear mRNA export plays an important role in gene expression. We describe the
mechanisms of mRNA export including the importance of mRNP assembly, docking with the …

Previous studies have led to the view that mRNAs are transported from the nucleus to the
cytoplasm by machinery that is conserved from yeast to humans. Moreover, this machinery is …