Neurite growth requires neurite extension and retraction, which are associated with protein
degradation. Autophagy is a conserved bulk degradation pathway that regulates several …

Remodeling of cytoskeleton structures, such as microtubule assembly, is believed to be
crucial for growth cone initiation and regrowth of injured axons. Autophagy plays important …

Emerging lines of evidence show that the mechanisms of neurite degeneration are
convergent, with poor neuritic transport, mitochondrial dysfunction and an increase in intra …

Macroautophagy/autophagy is essential for maintaining cellular homeostasis through the
degradation of organelles and proteins. It also has a prominent role in modulating aging …

Autophagy has recently emerged as potential drug target for prevention of
neurodegeneration. However, the details of the autophagy process and regulation in the …

In addition to the canonical role in protein homeostasis, autophagy has recently been found
to be involved in axonal dystrophy and neurodegeneration. Whether autophagy may also be …

Peripheral neuropathies can result in cytoskeletal changes in axons, ultimately leading to
Wallerian degeneration and cell death. Recently, autophagy has been studied as a potential …

Axon degeneration is a pathophysiological process of axonal dying and breakdown, which
is characterized by several morphological features including the accumulation of axoplasmic …

Autophagy, a regulated cellular degradation process responsible for the turnover of long-
lived proteins and organelles, has been increasingly implicated in neurological disorders …

Interstitial axon branching is an essential step during the establishment of neuronal
connectivity. However, the exact mechanisms on how the number and position of branches …