[HTML][HTML] Effects of Phosphoethanolamine Supplementation on Mitochondrial Activity and Lipogenesis in a Caffeine Ingestion Caenorhabditis elegans Model

H Min, E Youn, J Kim, SY Son, CH Lee, YH Shim - Nutrients, 2020 - mdpi.com
Caffeine intake is strongly linked to lipid metabolism. We previously reported the age-
dependent physiological effects of caffeine intake in a Caenorhabditis elegans model. Since …

Early-life caffeine exposure induces morphological changes and altered physiology in Caenorhabditis elegans

L Kuo-Esser, R Chen, K Lawson, K Kuchinski… - Biochemical and …, 2024 - Elsevier
Caffeine, a widely consumed stimulant, is known for its effects on alertness and fatigue
reduction by blockade of adenosine receptors. While it holds therapeutic potential, its …

[HTML][HTML] Caffeine Promotes Conversion of Palmitic Acid to Palmitoleic Acid by Inducing Expression of fat-5 in Caenorhabditis elegans and scd1 in Mice

X Du, Q Huang, Y Guan, M Lv, X He, C Fang… - Frontiers in …, 2018 - frontiersin.org
The synthesis and metabolism of fatty acids in an organism is related to many biological
processes and is involved in several diseases. The effects of caffeine on fatty acid synthesis …

[HTML][HTML] Long-term caffeine intake exerts protective effects on intestinal aging by regulating vitellogenesis and mitochondrial function in an aged Caenorhabditis …

H Min, E Youn, YH Shim - Nutrients, 2021 - mdpi.com
Caffeine, a methylxanthine derived from plants, is the most widely consumed ingredient in
daily life. Therefore, it is necessary to investigate the effects of caffeine intake on essential …

[HTML][HTML] High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans

J Alcántar-Fernández, A González-Maciel… - PLoS …, 2019 - journals.plos.org
Glucose is an important nutrient that dictates the development, fertility and lifespan of all
organisms. In humans, a deficit in its homeostatic control might lead to hyperglucemia and …

[HTML][HTML] Effects of High Dietary Carbohydrate and Lipid Intake on the Lifespan of C. elegans

B Franco-Juárez, S Gómez-Manzo… - Cells, 2021 - mdpi.com
Health and lifespan are influenced by dietary nutrients, whose balance is dependent on the
supply or demand of each organism. Many studies have shown that an increased …

Effects of epigallocatechin gallate, caffeine, and their combination on fat accumulation in high-glucose diet-fed Caenorhabditis elegans

C Guo, W Shen, W Jin, X Jia, Z Ji… - Bioscience …, 2023 - academic.oup.com
Epigallocatechin gallate (EGCG) and caffeine are inevitable to be ingested together in the
process of drinking green tea. This study used Caenorhabditis elegans as an organism …

Supplementation with phosphatidylethanolamine confers anti-oxidant and anti-aging effects via hormesis and reduced insulin/IGF-1-like signaling in C. elegans

S Park, BK Kim, SK Park - Mechanisms of Ageing and Development, 2021 - Elsevier
Phosphatidylethanolamine is a major component of phospholipids with both structural and
metabolic functions in cells. Previous studies have revealed that phosphatidylethanolamine …

[HTML][HTML] Caffeine induces the stress response and up-regulates heat shock proteins in Caenorhabditis elegans

M Al-Amin, I Kawasaki, J Gong, YH Shim - Molecules and cells, 2016 - Elsevier
Caffeine has both positive and negative effects on physiological functions in a dose-
dependent manner. C. elegans has been used as an animal model to investigate the effects …

Green coffee bean extract and 5-O-caffeoylquinic acid regulate fat metabolism in Caenorhabditis elegans

R Farias-Pereira, J Oshiro, KH Kim, Y Park - Journal of Functional Foods, 2018 - Elsevier
Green coffee bean extract (GCBE) and chlorogenic acids are known to be associated with
weight loss. 5-O-caffeoylquinic acid (5-CQA) is the main form of chlorogenic acid in GCBE …